CID 23724557

Details

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Internal ID 8db2d329-cdf8-49ac-94a6-83890730dd88
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 4-[[5-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-4,11-dimethyl-2-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C46H72N10O12/c1-8-9-11-18-34(57)50-31(24-36(59)60)40(62)54-38-27(6)68-45(67)37(26(4)5)53-41(63)32(23-28-15-12-10-13-16-28)55(7)44(66)33(22-25(2)3)56-35(58)20-19-30(43(56)65)52-39(61)29(51-42(38)64)17-14-21-49-46(47)48/h10,12-13,15-16,25-27,29-33,35,37-38,58H,8-9,11,14,17-24H2,1-7H3,(H,50,57)(H,51,64)(H,52,61)(H,53,63)(H,54,62)(H,59,60)(H4,47,48,49)
InChI Key XKZZUWLVOGBTLH-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C46H72N10O12
Molecular Weight 957.10 g/mol
Exact Mass 956.53311777 g/mol
Topological Polar Surface Area (TPSA) 334.00 Ų
XlogP 1.90

Synonyms

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CHEBI:80070
Q27149222
4-[[5-benzyl-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-4,11-dimethyl-2-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-3-(hexanoylamino)-4-oxobutanoic acid

2D Structure

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2D Structure of CID 23724557

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.95% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.21% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 99.17% 83.82%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.85% 99.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.01% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 97.10% 90.17%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 95.46% 92.08%
CHEMBL3837 P07711 Cathepsin L 94.10% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.06% 95.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 94.02% 97.64%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 92.34% 93.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 91.56% 90.71%
CHEMBL4072 P07858 Cathepsin B 91.36% 93.67%
CHEMBL4644 P41968 Melanocortin receptor 3 91.23% 99.52%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.62% 96.47%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 90.02% 95.89%
CHEMBL1949 P62937 Cyclophilin A 89.19% 98.57%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.02% 94.45%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.74% 99.23%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 88.54% 97.14%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 88.03% 88.42%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.88% 93.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.10% 86.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.03% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.98% 93.03%
CHEMBL3776 Q14790 Caspase-8 86.93% 97.06%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.79% 89.00%
CHEMBL3891 P07384 Calpain 1 85.52% 93.04%
CHEMBL4588 P22894 Matrix metalloproteinase 8 85.15% 94.66%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 84.93% 95.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 84.11% 98.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.87% 95.89%
CHEMBL5103 Q969S8 Histone deacetylase 10 83.43% 90.08%
CHEMBL3468 P55210 Caspase-7 82.95% 95.68%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.15% 100.00%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.04% 90.93%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 23724557
LOTUS LTS0069414
wikiData Q27149222