Chisomicine A

Details

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Internal ID c78d5255-f781-4291-bd15-0e948895c3b4
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Tricarboxylic acids and derivatives
IUPAC Name [(1R,2S,5R,6R,12Z,14R,15R,18S)-6-(furan-3-yl)-18-(2-methoxy-2-oxoethyl)-1,5,15-trimethyl-8,17-dioxo-7-oxatetracyclo[13.2.1.02,11.05,10]octadeca-10,12-dien-14-yl] (E)-2-methylbut-2-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H38O8/c1-7-18(2)29(36)39-25-9-8-20-21(32(5)23(15-26(34)37-6)31(25,4)16-24(32)33)10-12-30(3)22(20)14-27(35)40-28(30)19-11-13-38-17-19/h7-9,11,13,17,21,23,25,28H,10,12,14-16H2,1-6H3/b9-8-,18-7+/t21-,23-,25+,28-,30+,31+,32+/m0/s1
InChI Key XVHXALVCAPLJJX-TXTGMHMPSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C32H38O8
Molecular Weight 550.60 g/mol
Exact Mass 550.25666817 g/mol
Topological Polar Surface Area (TPSA) 109.00 Ų
XlogP 3.70

Synonyms

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RefChem:125224
((1R,2S,5R,6R,12Z,14R,15R,18S)-6-(furan-3-yl)-18-(2-methoxy-2-oxoethyl)-1,5,15-trimethyl-8,17-dioxo-7-oxatetracyclo(13.2.1.02,11.05,10)octadeca-10,12-dien-14-yl) (E)-2-methylbut-2-enoate
CHEMBL1782585
CHEBI:68095
Q27136585

2D Structure

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2D Structure of Chisomicine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.98% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.25% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.26% 96.09%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.78% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.86% 86.33%
CHEMBL2243 O00519 Anandamide amidohydrolase 89.61% 97.53%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.63% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.24% 95.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.17% 94.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.05% 99.17%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.49% 92.62%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.88% 100.00%
CHEMBL221 P23219 Cyclooxygenase-1 82.65% 90.17%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.50% 100.00%
CHEMBL1907601 P11802 Cyclin-dependent kinase 4/cyclin D1 82.37% 98.99%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.35% 95.89%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 82.30% 91.24%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.87% 97.09%
CHEMBL3401 O75469 Pregnane X receptor 81.30% 94.73%
CHEMBL255 P29275 Adenosine A2b receptor 81.24% 98.59%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 81.03% 100.00%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 80.98% 93.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.86% 89.00%
CHEMBL5028 O14672 ADAM10 80.44% 97.50%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 80.34% 94.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Chisocheton ceramicus

Cross-Links

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PubChem 53356104
NPASS NPC329180
ChEMBL CHEMBL1782585