Chiapenine ES-II

Details

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Internal ID 8a5722d2-39fc-4d9d-982d-58ae1068bcd4
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Terpene lactones
IUPAC Name [(1S,3R,18S,19R,20R,21S,22S,24R,25R,26S)-22,25-diacetyloxy-21-(acetyloxymethyl)-20-benzoyloxy-15,26-dihydroxy-3,15,26-trimethyl-6,16,23-trioxo-2,5,17-trioxa-11-azapentacyclo[16.7.1.01,21.03,24.07,12]hexacosa-7(12),8,10-trien-19-yl] benzoate
SMILES (Canonical) CC(=O)OCC12C(C(C3C(C14C(C(C(=O)C2OC(=O)C)C(O4)(COC(=O)C5=C(CCC(C(=O)O3)(C)O)N=CC=C5)C)OC(=O)C)(C)O)OC(=O)C6=CC=CC=C6)OC(=O)C7=CC=CC=C7
SMILES (Isomeric) CC(=O)OC[C@@]12[C@H]([C@H]([C@H]3[C@]([C@@]14[C@@H]([C@@H](C(=O)[C@H]2OC(=O)C)[C@@](O4)(COC(=O)C5=C(CCC(C(=O)O3)(C)O)N=CC=C5)C)OC(=O)C)(C)O)OC(=O)C6=CC=CC=C6)OC(=O)C7=CC=CC=C7
InChI InChI=1S/C46H47NO18/c1-24(48)58-23-45-35(61-26(3)50)32(51)31-34(60-25(2)49)46(45)44(6,57)36(33(62-38(52)27-14-9-7-10-15-27)37(45)63-39(53)28-16-11-8-12-17-28)64-41(55)42(4,56)20-19-30-29(18-13-21-47-30)40(54)59-22-43(31,5)65-46/h7-18,21,31,33-37,56-57H,19-20,22-23H2,1-6H3/t31-,33+,34-,35-,36+,37+,42?,43+,44+,45-,46+/m1/s1
InChI Key SFNVOEKFHBIHJA-BLEJTOHSSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C46H47NO18
Molecular Weight 901.90 g/mol
Exact Mass 901.27931365 g/mol
Topological Polar Surface Area (TPSA) 264.00 Ų
XlogP 2.50

Synonyms

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CHEMBL510337

2D Structure

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2D Structure of Chiapenine ES-II

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.17% 96.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 96.57% 86.33%
CHEMBL2581 P07339 Cathepsin D 96.45% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 96.27% 91.49%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 95.71% 95.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.49% 85.14%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.98% 99.23%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.35% 91.11%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 92.16% 81.11%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 90.51% 82.69%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 89.31% 94.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.88% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.17% 89.00%
CHEMBL2535 P11166 Glucose transporter 85.70% 98.75%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 85.06% 94.08%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 84.28% 96.00%
CHEMBL5028 O14672 ADAM10 84.26% 97.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 83.25% 93.00%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 83.08% 83.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.26% 91.07%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.12% 94.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 81.50% 97.25%
CHEMBL4208 P20618 Proteasome component C5 81.39% 90.00%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 80.37% 96.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11491470
LOTUS LTS0066247
wikiData Q105251893