Chelilutine

Details

Top
Internal ID 909d4901-c01b-41e4-953a-ee7a8d83c60c
Taxonomy Alkaloids and derivatives > Benzophenanthridine alkaloids > Quaternary benzophenanthridine alkaloids
IUPAC Name 1,2,4-trimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H20NO5/c1-23-10-15-20(18(24-2)9-19(25-3)22(15)26-4)13-6-5-12-7-16-17(28-11-27-16)8-14(12)21(13)23/h5-10H,11H2,1-4H3/q+1
InChI Key LZJHNXHYKRKCDZ-UHFFFAOYSA-N
Popularity 11 references in papers

Physical and Chemical Properties

Top
Molecular Formula C22H20NO5+
Molecular Weight 378.40 g/mol
Exact Mass 378.13414774 g/mol
Topological Polar Surface Area (TPSA) 50.00 Ų
XlogP 4.50

Synonyms

Top
C12229
1,2,4-trimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
AC1L9F2E
55950-32-8
CHEMBL4748098
CHEBI:31390
DTXSID001318159
Q27114299
[1,3]benzodioxolo[5,6-c]phenanthridinium, 1,2,4-trimethoxy-12-methyl-
1,2,4-trimethoxy-12-methyl-[1,3]benzodioxolo[6,5-c]phenanthridin-12-ium

2D Structure

Top
2D Structure of Chelilutine

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.58% 96.77%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.40% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.28% 94.45%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 92.19% 94.80%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.44% 94.00%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 90.01% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.44% 95.56%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 88.70% 89.62%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 88.58% 96.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.07% 86.33%
CHEMBL215 P09917 Arachidonate 5-lipoxygenase 86.62% 92.68%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 86.33% 96.09%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.50% 93.99%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 83.41% 94.03%
CHEMBL2535 P11166 Glucose transporter 82.99% 98.75%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 81.96% 85.30%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 80.51% 80.96%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Chelidonium majus
Eschscholzia californica
Sanguinaria canadensis
Stylophorum lasiocarpum

Cross-Links

Top
PubChem 443720
LOTUS LTS0192507
wikiData Q27114299