Chaxine B

Details

Top
Internal ID dc821fed-ad98-437b-8794-644d7bac297f
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Sesquiterpenoids
IUPAC Name (4-hydroxy-1-methyl-2-oxocyclohexyl) (2Z)-2-[(1R,3aR,7aR)-1-[(E)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-5-oxo-1,2,3,3a,6,7-hexahydroinden-4-ylidene]acetate
SMILES (Canonical) CC(C)C(C)C=CC(C)C1CCC2C1(CCC(=O)C2=CC(=O)OC3(CCC(CC3=O)O)C)C
SMILES (Isomeric) CC(C)C(C)/C=C/C(C)[C@H]1CC[C@@H]\2[C@@]1(CCC(=O)/C2=C\C(=O)OC3(CCC(CC3=O)O)C)C
InChI InChI=1S/C28H42O5/c1-17(2)18(3)7-8-19(4)22-9-10-23-21(24(30)12-13-27(22,23)5)16-26(32)33-28(6)14-11-20(29)15-25(28)31/h7-8,16-20,22-23,29H,9-15H2,1-6H3/b8-7+,21-16-/t18?,19?,20?,22-,23+,27-,28?/m1/s1
InChI Key HTXUAQKMNHGMFH-BUQUEDMSSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C28H42O5
Molecular Weight 458.60 g/mol
Exact Mass 458.30322444 g/mol
Topological Polar Surface Area (TPSA) 80.70 Ų
XlogP 5.10

Synonyms

Top
(4-hydroxy-1-methyl-2-oxocyclohexyl) (2Z)-2-((1R,3aR,7aR)-1-((E)-5,6-dimethylhept-3-en-2-yl)-7a-methyl-5-oxo-1,2,3,3a,6,7-hexahydroinden-4-ylidene)acetate
(4-hydroxy-1-methyl-2-oxocyclohexyl) (2Z)-2-[(1R,3aR,7aR)-1-[(E)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-5-oxo-1,2,3,3a,6,7-hexahydroinden-4-ylidene]acetate
RefChem:125088
1201264-22-3
CHEBI:215997

2D Structure

Top
2D Structure of Chaxine B

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 95.98% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.84% 91.11%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.59% 82.69%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.94% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.42% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.36% 96.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 89.22% 96.38%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.73% 95.56%
CHEMBL4072 P07858 Cathepsin B 88.56% 93.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 87.89% 93.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.73% 99.23%
CHEMBL299 P17252 Protein kinase C alpha 86.87% 98.03%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.39% 97.25%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.14% 91.07%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.53% 90.71%
CHEMBL5028 O14672 ADAM10 82.86% 97.50%
CHEMBL1937 Q92769 Histone deacetylase 2 82.41% 94.75%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.36% 100.00%
CHEMBL226 P30542 Adenosine A1 receptor 81.15% 95.93%
CHEMBL5600 P27448 Serine/threonine-protein kinase c-TAK1 80.85% 88.81%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.71% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.16% 95.89%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 139587340
LOTUS LTS0106096
wikiData Q77563665