Chaiyaphumine A

Details

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Internal ID bf1ba5e0-6e2e-49b1-8d10-329ccc2b92ac
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name N-[(3R,6R,9S,10R,13S,16S)-6-benzyl-13-(1H-indol-3-ylmethyl)-3,10-dimethyl-2,5,8,12,15-pentaoxo-11-oxa-1,4,7,14-tetrazabicyclo[14.3.0]nonadecan-9-yl]-2-phenylacetamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H44N6O7/c1-24-39(51)46-19-11-18-33(46)37(49)44-32(22-28-23-41-30-17-10-9-16-29(28)30)40(52)53-25(2)35(45-34(47)21-27-14-7-4-8-15-27)38(50)43-31(36(48)42-24)20-26-12-5-3-6-13-26/h3-10,12-17,23-25,31-33,35,41H,11,18-22H2,1-2H3,(H,42,48)(H,43,50)(H,44,49)(H,45,47)/t24-,25-,31-,32+,33+,35+/m1/s1
InChI Key YZLRYEXQPAXUDX-WRECJYPKSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C40H44N6O7
Molecular Weight 720.80 g/mol
Exact Mass 720.32714776 g/mol
Topological Polar Surface Area (TPSA) 179.00 Ų
XlogP 3.90

Synonyms

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CHEMBL3235373

2D Structure

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2D Structure of Chaiyaphumine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.33% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.15% 85.14%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 97.99% 97.64%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.54% 91.11%
CHEMBL333 P08253 Matrix metalloproteinase-2 96.01% 96.31%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.75% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.23% 96.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.92% 93.03%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.92% 99.23%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.39% 90.08%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 89.83% 90.71%
CHEMBL1902 P62942 FK506-binding protein 1A 89.73% 97.05%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.24% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.50% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.48% 97.09%
CHEMBL1951 P21397 Monoamine oxidase A 85.99% 91.49%
CHEMBL1741221 Q9Y4P1 Cysteine protease ATG4B 85.35% 87.50%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 84.71% 95.71%
CHEMBL5805 Q9NR97 Toll-like receptor 8 83.73% 96.25%
CHEMBL321 P14780 Matrix metalloproteinase 9 83.13% 92.12%
CHEMBL4644 P41968 Melanocortin receptor 3 83.09% 99.52%
CHEMBL3310 Q96DB2 Histone deacetylase 11 81.36% 88.56%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.23% 95.83%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 86302630
LOTUS LTS0204939
wikiData Q75058564