Cervimycin D

Details

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Internal ID f188f8c8-0fbc-402c-a18c-896b78d865f8
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name 3-[(2S,3S,6S)-6-[(2S,3S,6S)-6-[(2S,3S,6S)-6-[(2R,3S,6S)-6-[[(1R,4aS,12aR)-3-carbamoyl-4,6-dihydroxy-4a-[(2S,5S,6R)-5-[(2S,5S,6R)-5-hydroxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-9-methoxy-2,5,7,10-tetraoxo-12,12a-dihydro-1H-tetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-2-methyloxan-3-yl]oxy-2-methyloxan-3-yl]oxy-2-methyloxan-3-yl]oxy-2-methyl-3-oxopropanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C60H79NO25/c1-24(58(70)71)59(72)84-40-13-18-45(77-30(40)7)82-37-11-16-43(75-27(37)4)81-36-10-17-44(76-26(36)3)83-38-12-19-46(78-28(38)5)85-54-33-22-31-21-32-49(35(63)23-41(73-8)51(32)64)52(65)48(31)55(67)60(33,56(68)50(53(54)66)57(61)69)86-47-20-14-39(29(6)79-47)80-42-15-9-34(62)25(2)74-42/h21,23-30,33-34,36-40,42-47,54,62,65,68H,9-20,22H2,1-8H3,(H2,61,69)(H,70,71)/t24?,25-,26+,27+,28-,29-,30+,33-,34+,36+,37+,38+,39+,40+,42+,43+,44+,45+,46+,47+,54-,60-/m1/s1
InChI Key YQSUNUWAYVGFKR-DIMVSIEISA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C60H79NO25
Molecular Weight 1214.30 g/mol
Exact Mass 1213.49411701 g/mol
Topological Polar Surface Area (TPSA) 356.00 Ų
XlogP 6.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Cervimycin D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.73% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.79% 96.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.59% 96.38%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.07% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.99% 86.33%
CHEMBL2581 P07339 Cathepsin D 95.05% 98.95%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.53% 97.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.60% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.85% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.42% 95.56%
CHEMBL241 Q14432 Phosphodiesterase 3A 91.28% 92.94%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 90.43% 90.71%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 89.97% 96.00%
CHEMBL2179 P04062 Beta-glucocerebrosidase 88.61% 85.31%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.29% 99.23%
CHEMBL226 P30542 Adenosine A1 receptor 87.90% 95.93%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 87.77% 91.07%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 86.85% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.68% 100.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.60% 99.17%
CHEMBL3474 P14555 Phospholipase A2 group IIA 84.14% 94.05%
CHEMBL3864 Q06124 Protein-tyrosine phosphatase 2C 82.80% 94.42%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 82.63% 96.77%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.27% 97.14%
CHEMBL2535 P11166 Glucose transporter 81.72% 98.75%
CHEMBL340 P08684 Cytochrome P450 3A4 81.71% 91.19%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.52% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 54677926
LOTUS LTS0069281
wikiData Q75062834