Celangulin IV

Details

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Internal ID 74c75d7d-91be-48d8-a1f0-9681cc0d2e49
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Hexacarboxylic acids and derivatives
IUPAC Name [(1S,2S,4S,5R,6S,7S,8R,9R,12R)-4,5,8,12-tetraacetyloxy-2-hydroxy-2,10,10-trimethyl-6-(2-methylpropanoyloxymethyl)-11-oxatricyclo[7.2.1.01,6]dodecan-7-yl] benzoate
SMILES (Canonical) CC(C)C(=O)OCC12C(C(CC(C13C(C(C(C2OC(=O)C4=CC=CC=C4)OC(=O)C)C(O3)(C)C)OC(=O)C)(C)O)OC(=O)C)OC(=O)C
SMILES (Isomeric) CC(C)C(=O)OC[C@@]12[C@H]([C@H](C[C@]([C@@]13[C@@H]([C@@H]([C@H]([C@H]2OC(=O)C4=CC=CC=C4)OC(=O)C)C(O3)(C)C)OC(=O)C)(C)O)OC(=O)C)OC(=O)C
InChI InChI=1S/C34H44O14/c1-17(2)29(39)42-16-33-26(45-20(5)37)23(43-18(3)35)15-32(9,41)34(33)27(46-21(6)38)24(31(7,8)48-34)25(44-19(4)36)28(33)47-30(40)22-13-11-10-12-14-22/h10-14,17,23-28,41H,15-16H2,1-9H3/t23-,24+,25+,26-,27+,28+,32-,33-,34-/m0/s1
InChI Key ARLOYSQKSCYUOB-BGFKHHOWSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C34H44O14
Molecular Weight 676.70 g/mol
Exact Mass 676.27310607 g/mol
Topological Polar Surface Area (TPSA) 187.00 Ų
XlogP 2.60

Synonyms

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144409-63-2
Propanoic acid, 2-methyl-, ((3R,4R,5S,5aS,6R,7S,9S,9aS,10R)-4,6,7,10-tetrakis(acetyloxy)-5-(benzoyloxy)octahydro-9-hydroxy-2,2,9-trimethyl-5aH-3,9a-methano-1-benzoxepin-5a-yl)methyl ester
Propanoic acid, 2-methyl-, 94,6,7,10-tetrakis(acetyloxy)-5-(benzoyloxy)octahydro-9-hydroxy-2,2,9-trimethyl-5aH-3,9a-methano-1-benzoxepin-5a-yl)methyl ester, (3R-(3alpha,4alpha,5alpha,5aalpha,6 alpha,7alpha,9beta,9aalpha,10R*))-

2D Structure

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2D Structure of Celangulin IV

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.04% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 97.22% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.06% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.61% 98.95%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.26% 86.33%
CHEMBL2996 Q05655 Protein kinase C delta 90.80% 97.79%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 85.80% 95.56%
CHEMBL5028 O14672 ADAM10 84.84% 97.50%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.69% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.54% 99.23%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 83.41% 94.08%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 83.21% 83.00%
CHEMBL4208 P20618 Proteasome component C5 83.10% 90.00%
CHEMBL1951 P21397 Monoamine oxidase A 82.74% 91.49%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 82.23% 94.62%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.67% 91.07%
CHEMBL340 P08684 Cytochrome P450 3A4 81.32% 91.19%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 81.00% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Celastrus angulata

Cross-Links

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PubChem 44149142
LOTUS LTS0129132
wikiData Q104917405