15-hydroxy-17-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo(c)(1)oxacyclotetradecine-1,11(12H)-dione

Details

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Internal ID 6efb6df8-0b44-4d9a-b484-6c0050f188a7
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (4R)-16-hydroxy-18-methoxy-4-methyl-3-oxabicyclo[12.4.0]octadeca-1(14),15,17-triene-2,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C19H26O5/c1-13-8-6-4-3-5-7-9-15(20)10-14-11-16(21)12-17(23-2)18(14)19(22)24-13/h11-13,21H,3-10H2,1-2H3/t13-/m1/s1
InChI Key OWHJIFBGXNKCCV-CYBMUJFWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C19H26O5
Molecular Weight 334.40 g/mol
Exact Mass 334.17802393 g/mol
Topological Polar Surface Area (TPSA) 72.80 Ų
XlogP 3.90

Synonyms

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(4R)-16-hydroxy-18-methoxy-4-methyl-3-oxabicyclo(12.4.0)octadeca-1(14),15,17-triene-2,12-dione
15-hydroxy-17-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo(c)(1)oxacyclotetradecine-1,11(12H)-dione
15-hydroxy-17-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo[c][1]oxacyclotetradecine-1,11(12H)-dione
RefChem:78796
15-hydroxy-17-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo[c ][1]oxacyclotetradecine-1,11(12H)-dione
CHEBI:203944

2D Structure

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2D Structure of 15-hydroxy-17-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo(c)(1)oxacyclotetradecine-1,11(12H)-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.66% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.24% 95.56%
CHEMBL2581 P07339 Cathepsin D 94.62% 98.95%
CHEMBL241 Q14432 Phosphodiesterase 3A 90.50% 92.94%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.29% 86.33%
CHEMBL1951 P21397 Monoamine oxidase A 90.02% 91.49%
CHEMBL2535 P11166 Glucose transporter 89.75% 98.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.66% 96.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.40% 92.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.01% 95.89%
CHEMBL5203 P33316 dUTP pyrophosphatase 86.83% 99.18%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.47% 97.09%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.13% 99.17%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 85.29% 96.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.51% 94.00%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 84.51% 82.67%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.77% 97.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.51% 94.45%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 82.44% 96.21%
CHEMBL217 P14416 Dopamine D2 receptor 82.01% 95.62%
CHEMBL3192 Q9BY41 Histone deacetylase 8 81.75% 93.99%
CHEMBL253 P34972 Cannabinoid CB2 receptor 81.40% 97.25%
CHEMBL340 P08684 Cytochrome P450 3A4 80.81% 91.19%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.80% 89.00%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 80.55% 94.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 122369885
LOTUS LTS0081848
wikiData Q77382192