Carinatumins B (2)

Details

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Internal ID 5bffa8ee-2a21-4cf3-b3bc-51fb47eddf44
Taxonomy Organoheterocyclic compounds > Phenanthrolines
IUPAC Name (1R,9R,10R,11R)-11-hydroxy-16-methyl-6,14-diazatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,16-trien-5-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C16H20N2O2/c1-9-6-10-7-12-11(2-3-14(20)18-12)16(8-9)15(10)13(19)4-5-17-16/h2-3,6,10,13,15,17,19H,4-5,7-8H2,1H3,(H,18,20)/t10-,13+,15-,16-/m0/s1
InChI Key RGJUWLMFRYLAOJ-UXVLEFJLSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C16H20N2O2
Molecular Weight 272.34 g/mol
Exact Mass 272.152477885 g/mol
Topological Polar Surface Area (TPSA) 61.40 Ų
XlogP -0.30

Synonyms

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CHEMBL241838
BDBM50201170

2D Structure

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2D Structure of Carinatumins B (2)

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL220 P22303 Acetylcholinesterase 97.42% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.17% 85.14%
CHEMBL1937 Q92769 Histone deacetylase 2 94.74% 94.75%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.06% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.46% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.39% 95.56%
CHEMBL2581 P07339 Cathepsin D 92.94% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.41% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.25% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 87.81% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.88% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.71% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.41% 100.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 84.34% 93.99%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 82.11% 93.04%
CHEMBL5103 Q969S8 Histone deacetylase 10 81.87% 90.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 44428320
LOTUS LTS0074203
wikiData Q105235914