Caniferolide B

Details

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Internal ID ebbe0867-ca2d-4e72-a3e4-928bdb5cb411
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name [(2R,3S,6S)-6-[(2S,3R,4R,6R)-6-[(3S,4R,5R,6R,7S,8S)-5,7-dihydroxy-4,6-dimethyl-8-[(1R,3S,5R,7R,11S,12S,14S,15R,16R,21S,22R,24R,28R,31R,32S,34R,35R,36S)-3,5,7,11,22,24,28,32,34,35,36-undecahydroxy-15,21,31-trimethyl-18,33-dioxo-13,17,38-trioxatricyclo[32.3.1.012,14]octatriacont-19-en-16-yl]nonan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl]oxy-2-methyloxan-3-yl] (2R,3S)-3-hydroxy-2-methyl-3-(6-methyl-5,8-dioxonaphthalen-2-yl)propanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C77H122O28/c1-13-59(100-63-35-76(12,96)74(45(11)99-63)103-62-27-25-60(44(10)98-62)101-75(95)42(8)68(92)46-22-24-53-54(29-46)57(85)28-38(4)64(53)88)39(5)66(90)40(6)67(91)41(7)69-43(9)70-71(104-70)55(83)19-15-18-48(79)30-50(81)31-51(82)32-52-34-58(86)72(93)77(97,105-52)73(94)65(89)37(3)20-23-47(78)16-14-17-49(80)33-56(84)36(2)21-26-61(87)102-69/h21-22,24,26,28-29,36-37,39-45,47-52,55-56,58-60,62-63,65-72,74,78-84,86,89-93,96-97H,13-20,23,25,27,30-35H2,1-12H3/t36-,37+,39-,40+,41-,42+,43+,44+,45-,47+,48+,49+,50+,51-,52+,55-,56+,58-,59-,60-,62-,63-,65-,66-,67-,68-,69+,70-,71-,72+,74+,76+,77+/m0/s1
InChI Key FEQOXSQEYWVXDK-PHXRGBFDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C77H122O28
Molecular Weight 1495.80 g/mol
Exact Mass 1494.81226323 g/mol
Topological Polar Surface Area (TPSA) 466.00 Ų
XlogP 3.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Caniferolide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 99.76% 97.25%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 99.41% 96.38%
CHEMBL2581 P07339 Cathepsin D 98.74% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.84% 96.09%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 97.83% 96.77%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.76% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.23% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 96.20% 97.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 95.49% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 95.46% 89.00%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 94.75% 95.52%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.17% 91.11%
CHEMBL4208 P20618 Proteasome component C5 94.00% 90.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 93.20% 91.07%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 92.98% 95.17%
CHEMBL226 P30542 Adenosine A1 receptor 91.82% 95.93%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.77% 97.14%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 91.53% 96.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.49% 95.89%
CHEMBL218 P21554 Cannabinoid CB1 receptor 88.75% 96.61%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 88.57% 97.31%
CHEMBL3359 P21462 Formyl peptide receptor 1 88.56% 93.56%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.49% 93.03%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 88.43% 96.47%
CHEMBL2413 P32246 C-C chemokine receptor type 1 87.84% 89.50%
CHEMBL240 Q12809 HERG 86.20% 89.76%
CHEMBL2996 Q05655 Protein kinase C delta 85.96% 97.79%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 85.57% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.11% 100.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.83% 96.90%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.27% 100.00%
CHEMBL268 P43235 Cathepsin K 84.18% 96.85%
CHEMBL3401 O75469 Pregnane X receptor 83.86% 94.73%
CHEMBL3437 Q16853 Amine oxidase, copper containing 83.81% 94.00%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 83.78% 90.24%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 83.22% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.15% 90.71%
CHEMBL2535 P11166 Glucose transporter 83.07% 98.75%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.90% 99.23%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 82.45% 83.00%
CHEMBL5028 O14672 ADAM10 82.42% 97.50%
CHEMBL3922 P50579 Methionine aminopeptidase 2 82.01% 97.28%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.87% 96.67%
CHEMBL5255 O00206 Toll-like receptor 4 81.18% 92.50%
CHEMBL340 P08684 Cytochrome P450 3A4 81.01% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682265
LOTUS LTS0069569
wikiData Q104994132