Callipeltin A

Details

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Internal ID 81e354e2-51e8-49d5-8fd2-b3180b343c89
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2R,3S,4S)-N'-[(3S,6R,9S,12S,15R,18S,21S,22R)-9-(3-amino-3-oxopropyl)-15-[3-(diaminomethylideneamino)propyl]-18-[(1R)-1-hydroxyethyl]-6-[(R)-(4-hydroxyphenyl)-methoxymethyl]-3,4,10,22-tetramethyl-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1-oxa-4,7,10,13,16,19-hexazacyclodocos-21-yl]-4-[[(2R,3R,4S)-7-(diaminomethylideneamino)-2,3-dihydroxy-4-[[(2R)-2-[[(2R,3R,4R)-3-hydroxy-2,4,6-trimethylheptanoyl]amino]propanoyl]amino]heptanoyl]amino]-2,3-dimethylpentanediamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C68H116N18O20/c1-30(2)28-32(5)51(90)35(8)56(94)77-36(9)57(95)78-42(18-16-26-75-67(71)72)52(91)53(92)63(101)81-47(33(6)34(7)55(70)93)60(98)83-49-39(12)106-66(104)37(10)85(13)65(103)50(54(105-15)40-20-22-41(88)23-21-40)84-59(97)45(24-25-46(69)89)86(14)64(102)44(29-31(3)4)80-58(96)43(19-17-27-76-68(73)74)79-61(99)48(38(11)87)82-62(49)100/h20-23,30-39,42-45,47-54,87-88,90-92H,16-19,24-29H2,1-15H3,(H2,69,89)(H2,70,93)(H,77,94)(H,78,95)(H,79,99)(H,80,96)(H,81,101)(H,82,100)(H,83,98)(H,84,97)(H4,71,72,75)(H4,73,74,76)/t32-,33+,34-,35-,36-,37+,38-,39-,42+,43-,44+,45+,47+,48+,49+,50-,51-,52-,53-,54-/m1/s1
InChI Key UDTRUOCOOZKCCT-QVVVRIHHSA-N
Popularity 16 references in papers

Physical and Chemical Properties

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Molecular Formula C68H116N18O20
Molecular Weight 1505.80 g/mol
Exact Mass 1504.86132816 g/mol
Topological Polar Surface Area (TPSA) 625.00 Ų
XlogP -2.90

Synonyms

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CHEBI:65556
Q27134009

2D Structure

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2D Structure of Callipeltin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.64% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.57% 96.09%
CHEMBL3837 P07711 Cathepsin L 99.12% 96.61%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.54% 91.11%
CHEMBL255 P29275 Adenosine A2b receptor 97.53% 98.59%
CHEMBL3060 Q9Y345 Glycine transporter 2 96.45% 99.17%
CHEMBL2094135 Q96BI3 Gamma-secretase 95.56% 98.05%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 94.67% 97.31%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 94.43% 90.93%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 93.44% 90.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.23% 97.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.76% 95.56%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 90.86% 89.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.55% 93.56%
CHEMBL4072 P07858 Cathepsin B 90.43% 93.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 90.12% 100.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 89.20% 85.00%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 88.54% 88.42%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 88.37% 96.47%
CHEMBL1949 P62937 Cyclophilin A 87.78% 98.57%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 87.76% 96.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 87.71% 96.90%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 87.63% 96.25%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.93% 85.14%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 86.60% 95.00%
CHEMBL2514 O95665 Neurotensin receptor 2 86.30% 100.00%
CHEMBL2413 P32246 C-C chemokine receptor type 1 84.53% 89.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.91% 94.45%
CHEMBL236 P41143 Delta opioid receptor 83.48% 99.35%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.83% 99.23%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 82.65% 96.67%
CHEMBL4040 P28482 MAP kinase ERK2 82.57% 83.82%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 82.50% 89.62%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 82.48% 100.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 82.09% 93.10%
CHEMBL4588 P22894 Matrix metalloproteinase 8 81.98% 94.66%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.87% 89.00%
CHEMBL4578 Q14680 Maternal embryonic leucine zipper kinase 81.35% 81.58%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.33% 95.89%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 80.72% 100.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.55% 90.08%
CHEMBL332 P03956 Matrix metalloproteinase-1 80.45% 94.50%
CHEMBL340 P08684 Cytochrome P450 3A4 80.44% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 70678682
LOTUS LTS0241584
wikiData Q27134009