Sulfurmycin B

Details

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Internal ID ba46b9c0-1a7d-43ec-8bcc-36d7bfe52be1
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name methyl 4-[4-(dimethylamino)-5-[(5,14-dimethyl-6-oxo-2,4,9,13-tetraoxatricyclo[8.4.0.03,8]tetradecan-12-yl)oxy]-6-methyloxan-2-yl]oxy-2,5,7-trihydroxy-6,11-dioxo-2-(2-oxopropyl)-3,4-dihydro-1H-tetracene-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C43H51NO16/c1-17(45)15-43(52)16-29(33-22(35(43)41(51)53-7)11-23-34(38(33)50)37(49)32-21(36(23)48)9-8-10-25(32)46)58-30-12-24(44(5)6)39(19(3)54-30)59-31-14-27-40(20(4)55-31)60-42-28(57-27)13-26(47)18(2)56-42/h8-11,18-20,24,27-31,35,39-40,42,46,50,52H,12-16H2,1-7H3
InChI Key DONDQYGRHMLYMF-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C43H51NO16
Molecular Weight 837.90 g/mol
Exact Mass 837.32078454 g/mol
Topological Polar Surface Area (TPSA) 223.00 Ų
XlogP 2.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Sulfurmycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.86% 91.11%
CHEMBL2581 P07339 Cathepsin D 98.77% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.52% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 97.73% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.11% 85.14%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 95.50% 96.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.30% 99.23%
CHEMBL340 P08684 Cytochrome P450 3A4 93.00% 91.19%
CHEMBL226 P30542 Adenosine A1 receptor 92.08% 95.93%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.04% 86.33%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.81% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.87% 95.89%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.95% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.88% 92.62%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 87.70% 96.21%
CHEMBL4208 P20618 Proteasome component C5 86.88% 90.00%
CHEMBL3401 O75469 Pregnane X receptor 86.66% 94.73%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.28% 99.17%
CHEMBL1951 P21397 Monoamine oxidase A 83.35% 91.49%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 83.15% 96.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.52% 100.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.11% 94.00%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 81.26% 83.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.01% 90.71%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 80.80% 96.95%
CHEMBL3788 O00444 Serine/threonine-protein kinase PLK4 80.69% 83.65%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 80.25% 96.67%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.12% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 12850476
LOTUS LTS0134761
wikiData Q104986070