Capsimycin

Details

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Internal ID 0f18c2f9-9402-45b2-beb6-c6f231261577
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Monoterpenoids > Iridoids and derivatives
IUPAC Name (3E,5S,8R,10R,13R,15R,17S,19Z,26S)-2-hydroxy-11-[(1S)-1-methoxyethyl]-10-methyl-14-oxa-22,27-diazahexacyclo[24.2.1.05,17.07,16.08,12.013,15]nonacosa-1,3,19-triene-21,28,29-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H40N2O6/c1-14-12-18-19-13-16-9-10-21(33)26-27(35)20(32-30(26)36)7-5-11-31-22(34)8-4-6-17(16)24(19)28-29(38-28)25(18)23(14)15(2)37-3/h4,8-10,14-20,23-25,28-29,33H,5-7,11-13H2,1-3H3,(H,31,34)(H,32,36)/b8-4-,10-9+,26-21?/t14-,15+,16-,17+,18-,19?,20+,23?,24?,25?,28-,29-/m1/s1
InChI Key IHWQOSNPTRXOEB-UPYCPYLXSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C30H40N2O6
Molecular Weight 524.60 g/mol
Exact Mass 524.28863700 g/mol
Topological Polar Surface Area (TPSA) 117.00 Ų
XlogP 3.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Capsimycin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.04% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.77% 97.25%
CHEMBL2581 P07339 Cathepsin D 96.18% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.21% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.92% 96.09%
CHEMBL1937 Q92769 Histone deacetylase 2 94.84% 94.75%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.50% 97.09%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 93.79% 96.21%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 92.69% 92.88%
CHEMBL5103 Q969S8 Histone deacetylase 10 91.99% 90.08%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 90.46% 91.07%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 90.09% 85.14%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.69% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.00% 89.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.37% 93.03%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.88% 96.77%
CHEMBL213 P08588 Beta-1 adrenergic receptor 83.28% 95.56%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 82.74% 99.15%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.45% 100.00%
CHEMBL5255 O00206 Toll-like receptor 4 82.17% 92.50%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 81.73% 95.71%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.18% 92.62%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.07% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.79% 97.14%
CHEMBL1978 P11511 Cytochrome P450 19A1 80.67% 91.76%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 80.44% 95.64%
CHEMBL340 P08684 Cytochrome P450 3A4 80.42% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589130
LOTUS LTS0039149
wikiData Q105113285