Slagenin B

Details

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Internal ID 64293752-0ec5-4f53-b237-552b943907cf
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Carboxylic acid derivatives > Carboxylic acid amides > 2-heteroaryl carboxamides
IUPAC Name N-[[(3aS,5S,6aR)-3a-methoxy-2-oxo-3,5,6,6a-tetrahydro-1H-furo[2,3-d]imidazol-5-yl]methyl]-4-bromo-1H-pyrrole-2-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C12H15BrN4O4/c1-20-12-9(16-11(19)17-12)3-7(21-12)5-15-10(18)8-2-6(13)4-14-8/h2,4,7,9,14H,3,5H2,1H3,(H,15,18)(H2,16,17,19)/t7-,9+,12-/m0/s1
InChI Key NMYWRAJXOWKTDP-VMAXQDLPSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C12H15BrN4O4
Molecular Weight 359.18 g/mol
Exact Mass 358.02767 g/mol
Topological Polar Surface Area (TPSA) 104.00 Ų
XlogP 0.00

Synonyms

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RefChem:931852
246137-00-8
N-(((3aR,5R,6aR)-6a-methoxy-2-oxo-3,3a,5,6-tetrahydro-1H-furo(2,3-d)imidazol-5-yl)methyl)-4-bromo-1H-pyrrole-2-carboxamide
N-(((3aS,5S,6aR)-3a-methoxy-2-oxo-3,5,6,6a-tetrahydro-1H-furo(2,3-d)imidazol-5-yl)methyl)-4-bromo-1H-pyrrole-2-carboxamide

2D Structure

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2D Structure of Slagenin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.26% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.61% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.67% 96.09%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.22% 97.09%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 90.09% 92.88%
CHEMBL2581 P07339 Cathepsin D 89.68% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.35% 94.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 88.98% 91.07%
CHEMBL4208 P20618 Proteasome component C5 88.80% 90.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.51% 97.25%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 84.96% 89.34%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.15% 99.23%
CHEMBL3401 O75469 Pregnane X receptor 83.90% 94.73%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.13% 95.56%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.21% 93.03%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 80.96% 80.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.66% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.59% 85.14%
CHEMBL3922 P50579 Methionine aminopeptidase 2 80.37% 97.28%
CHEMBL3230 O95977 Sphingosine 1-phosphate receptor Edg-6 80.31% 94.01%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 100982103
LOTUS LTS0074115
wikiData Q105182020