C-17-epi-Deoxy-0,8-salinomycin

Details

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Internal ID 60e4b19a-0eb5-4a37-8489-4e5ace77d7dc
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Terpene glycosides > Diterpene glycosides
IUPAC Name (2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41?,42-/m0/s1
InChI Key KQXDHUJYNAXLNZ-IBKCOUPJSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C42H70O11
Molecular Weight 751.00 g/mol
Exact Mass 750.49181304 g/mol
Topological Polar Surface Area (TPSA) 161.00 Ų
XlogP 5.70

Synonyms

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(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
(2R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((2S,5S,9S,10S,12R,15R)-2-((2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-methyloxan-2-yl)butanoate
(2R)-2-((2R,5S,6R)-6-((2S,3S,4S,6R)-6-((3S,5S,9S,10S,12R,15R)-3-((2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl)-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro(4.1.57.35)pentadec-13-en-9-yl)-3-hydroxy-4-methyl-5-oxooctan-2-yl)-5-methyloxan-2-yl)butanoic acid
(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(2S,5S,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoate
RefChem:122475
SALINOMYCIN, SODIUM
Spectrum_000093
Spectrum2_000073
Spectrum3_001999
Spectrum4_000224
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of C-17-epi-Deoxy-0,8-salinomycin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.56% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 96.63% 90.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.62% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.90% 97.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.84% 91.11%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 93.84% 96.21%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.47% 97.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 92.08% 96.38%
CHEMBL2581 P07339 Cathepsin D 91.94% 98.95%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.96% 100.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 87.21% 96.77%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.71% 93.56%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.22% 96.47%
CHEMBL340 P08684 Cytochrome P450 3A4 85.79% 91.19%
CHEMBL2413 P32246 C-C chemokine receptor type 1 85.09% 89.50%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.87% 97.14%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.86% 99.23%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 84.34% 96.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.15% 96.95%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 84.03% 92.29%
CHEMBL218 P21554 Cannabinoid CB1 receptor 83.18% 96.61%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.00% 89.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.88% 95.50%
CHEMBL4040 P28482 MAP kinase ERK2 82.64% 83.82%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.11% 91.07%
CHEMBL3837 P07711 Cathepsin L 81.50% 96.61%
CHEMBL5028 O14672 ADAM10 80.89% 97.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.38% 94.45%
CHEMBL4208 P20618 Proteasome component C5 80.22% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6602450
LOTUS LTS0079171
wikiData Q77280582