Brunsvicamide C

Details

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Internal ID 4c4ef31b-3095-4a57-9968-b6cc4afd2381
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (2R,3R)-2-[[(3S,6R,9S,12S,15S)-3-benzyl-6-[2-(2-formamidophenyl)-2-oxoethyl]-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid
SMILES (Canonical) CCC(C)C(C(=O)O)NC(=O)NC1CCCCNC(=O)C(NC(=O)C(N(C(=O)C(NC(=O)C(NC1=O)C(C)C)CC(C)C)C)CC(=O)C2=CC=CC=C2NC=O)CC3=CC=CC=C3
SMILES (Isomeric) CC[C@@H](C)[C@H](C(=O)O)NC(=O)N[C@H]1CCCCNC(=O)[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)CC(C)C)C)CC(=O)C2=CC=CC=C2NC=O)CC3=CC=CC=C3
InChI InChI=1S/C45H64N8O10/c1-8-28(6)38(44(61)62)52-45(63)50-32-20-14-15-21-46-39(56)33(23-29-16-10-9-11-17-29)48-41(58)35(24-36(55)30-18-12-13-19-31(30)47-25-54)53(7)43(60)34(22-26(2)3)49-42(59)37(27(4)5)51-40(32)57/h9-13,16-19,25-28,32-35,37-38H,8,14-15,20-24H2,1-7H3,(H,46,56)(H,47,54)(H,48,58)(H,49,59)(H,51,57)(H,61,62)(H2,50,52,63)/t28-,32+,33+,34+,35-,37+,38-/m1/s1
InChI Key HQMATMGVGJKSPD-MMHNDARSSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C45H64N8O10
Molecular Weight 877.00 g/mol
Exact Mass 876.47454027 g/mol
Topological Polar Surface Area (TPSA) 261.00 Ų
XlogP 4.60

Synonyms

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DTXSID101335255

2D Structure

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2D Structure of Brunsvicamide C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.94% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.99% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 97.57% 90.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 97.38% 93.00%
CHEMBL4040 P28482 MAP kinase ERK2 97.32% 83.82%
CHEMBL226 P30542 Adenosine A1 receptor 93.32% 95.93%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 92.76% 88.42%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.46% 95.56%
CHEMBL268 P43235 Cathepsin K 91.54% 96.85%
CHEMBL4072 P07858 Cathepsin B 90.60% 93.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.58% 93.56%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 88.65% 97.64%
CHEMBL5103 Q969S8 Histone deacetylase 10 87.81% 90.08%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 87.60% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.57% 97.09%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 87.47% 95.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.34% 93.03%
CHEMBL3202 P48147 Prolyl endopeptidase 87.16% 90.65%
CHEMBL1949 P62937 Cyclophilin A 86.62% 98.57%
CHEMBL2413 P32246 C-C chemokine receptor type 1 85.91% 89.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 85.58% 94.45%
CHEMBL2096618 P11274 Bcr/Abl fusion protein 85.43% 85.83%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.43% 97.14%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 85.37% 98.33%
CHEMBL4227 P25090 Lipoxin A4 receptor 85.22% 100.00%
CHEMBL3310 Q96DB2 Histone deacetylase 11 84.90% 88.56%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 83.31% 89.34%
CHEMBL4208 P20618 Proteasome component C5 82.49% 90.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.20% 99.23%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 81.43% 89.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.41% 90.71%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 81.37% 92.67%
CHEMBL2535 P11166 Glucose transporter 81.21% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682035
LOTUS LTS0075811
wikiData Q105032307