Brugine

Details

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Internal ID 62f5791b-a007-4d5d-a449-e2dae0cc9907
Taxonomy Alkaloids and derivatives > Tropane alkaloids
IUPAC Name (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) (3S)-dithiolane-3-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C12H19NO2S2/c1-13-8-2-3-9(13)7-10(6-8)15-12(14)11-4-5-16-17-11/h8-11H,2-7H2,1H3/t8?,9?,10?,11-/m0/s1
InChI Key BOJOZZSCQUTEBY-QUBJWBRDSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C12H19NO2S2
Molecular Weight 273.40 g/mol
Exact Mass 273.08572120 g/mol
Topological Polar Surface Area (TPSA) 80.10 Ų
XlogP 2.20

Synonyms

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14912-30-2
(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) (3S)-dithiolane-3-carboxylate
DTXSID00332035
(8-methyl-8-azabicyclo(3.2.1)octan-3-yl) (3S)-dithiolane-3-carboxylate
RefChem:121743
DTXCID50283129
C10849
8-Methyl-8-azabicyclo[3.2.1]octan-3-yl (3S)-1,2-dithiolane-3-carboxylate
AC1L9DTW
CHEBI:3194
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Brugine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.06% 96.09%
CHEMBL340 P08684 Cytochrome P450 3A4 90.93% 91.19%
CHEMBL238 Q01959 Dopamine transporter 90.83% 95.88%
CHEMBL1899 P46098 Serotonin 3a (5-HT3a) receptor 89.97% 100.00%
CHEMBL245 P20309 Muscarinic acetylcholine receptor M3 89.22% 97.53%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.08% 97.25%
CHEMBL4040 P28482 MAP kinase ERK2 87.51% 83.82%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 87.12% 96.95%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 86.49% 97.47%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 86.00% 97.21%
CHEMBL211 P08172 Muscarinic acetylcholine receptor M2 85.95% 94.97%
CHEMBL2581 P07339 Cathepsin D 85.22% 98.95%
CHEMBL4072 P07858 Cathepsin B 84.45% 93.67%
CHEMBL284 P27487 Dipeptidyl peptidase IV 83.11% 95.69%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.82% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 442998
LOTUS LTS0135461
wikiData Q27105983