Bispolide A2

Details

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Internal ID bf882e8b-460f-4b87-8dac-0a5084ae925e
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name 10-[4-[4-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-5-ethyl-2-hydroxy-6-methyloxan-2-yl]-3-hydroxybutan-2-yl]-20-[4-[4-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-5-ethyl-2-methoxy-6-methyloxan-2-yl]-3-hydroxybutan-2-yl]-5,9,15,19-tetraethyl-1,11-dioxacycloicosa-3,5,7,13,15,17-hexaene-2,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C63H102O18/c1-14-42-22-20-24-44(16-3)60(36(7)50(66)32-62(72)34-52(46(18-5)38(9)80-62)76-56-30-48(64)58(70)40(11)74-56)78-54(68)28-26-43(15-2)23-21-25-45(17-4)61(79-55(69)29-27-42)37(8)51(67)33-63(73-13)35-53(47(19-6)39(10)81-63)77-57-31-49(65)59(71)41(12)75-57/h20-29,36-41,44-53,56-61,64-67,70-72H,14-19,30-35H2,1-13H3
InChI Key OFYLDDSYNNQGMR-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C63H102O18
Molecular Weight 1147.50 g/mol
Exact Mass 1146.70661640 g/mol
Topological Polar Surface Area (TPSA) 259.00 Ų
XlogP 9.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Bispolide A2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.80% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.62% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.04% 91.11%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.82% 97.25%
CHEMBL2581 P07339 Cathepsin D 93.34% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.34% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.20% 97.09%
CHEMBL226 P30542 Adenosine A1 receptor 91.03% 95.93%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 90.52% 96.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.62% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.11% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.92% 95.89%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.50% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.85% 86.33%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 84.16% 92.86%
CHEMBL2842 P42345 Serine/threonine-protein kinase mTOR 83.67% 92.78%
CHEMBL221 P23219 Cyclooxygenase-1 83.63% 90.17%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.48% 100.00%
CHEMBL1871 P10275 Androgen Receptor 83.44% 96.43%
CHEMBL255 P29275 Adenosine A2b receptor 83.35% 98.59%
CHEMBL4072 P07858 Cathepsin B 82.05% 93.67%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.40% 96.47%
CHEMBL3572 P11597 Cholesteryl ester transfer protein 81.22% 92.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 81.14% 100.00%
CHEMBL4208 P20618 Proteasome component C5 81.02% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 91402214
LOTUS LTS0211145
wikiData Q105254273