Bengamide B

Details

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Internal ID c52dd514-ff8d-4608-9631-d06a64d8e3bb
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > N-acyl-alpha amino acids and derivatives
IUPAC Name [(3S,6S)-1-methyl-7-oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methylnon-6-enoyl]amino]azepan-3-yl] tetradecanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H58N2O8/c1-6-7-8-9-10-11-12-13-14-15-16-17-27(36)42-24-19-20-25(32(40)34(4)22-24)33-31(39)30(41-5)29(38)28(37)26(35)21-18-23(2)3/h18,21,23-26,28-30,35,37-38H,6-17,19-20,22H2,1-5H3,(H,33,39)/b21-18+/t24-,25-,26+,28-,29+,30+/m0/s1
InChI Key PFRKTXMXGDERHT-UCDUEDMDSA-N
Popularity 12 references in papers

Physical and Chemical Properties

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Molecular Formula C32H58N2O8
Molecular Weight 598.80 g/mol
Exact Mass 598.41931681 g/mol
Topological Polar Surface Area (TPSA) 146.00 Ų
XlogP 6.00

Synonyms

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104947-69-5
[(3S,6S)-1-methyl-7-oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methylnon-6-enoyl]amino]azepan-3-yl] tetradecanoate
BengamideB
SCHEMBL909970
CHEMBL446079
AKOS025142071
J-001295
(6E)-6,7,8,9-Tetradeoxy-N-[(3S,6S)-hexahydro-1-methyl-2-oxo-6-[(1-oxotetradecyl)oxy]-1H-azepin-3-yl]-8-methyl-2-O-methyl-D-gulo-Non-6-enonamide
[(3S,6S)-1-methyl-7-oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl]amino]azepan-3-yl] tetradecanoate
6-((4S,2R,3R,5R)-3,4,5-Trihydroxy-2-methoxy-8-methylnon-6-enoylamino)(3S,6S)-1-methyl-7-oxoazaperhydroepin-3-yl tetradecanoate

2D Structure

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2D Structure of Bengamide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.23% 96.09%
CHEMBL2581 P07339 Cathepsin D 98.96% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.82% 97.25%
CHEMBL3060 Q9Y345 Glycine transporter 2 96.98% 99.17%
CHEMBL321 P14780 Matrix metalloproteinase 9 94.26% 92.12%
CHEMBL230 P35354 Cyclooxygenase-2 94.19% 89.63%
CHEMBL5255 O00206 Toll-like receptor 4 93.07% 92.50%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 92.21% 100.00%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 91.23% 95.71%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 90.45% 97.29%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 90.08% 95.34%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 89.95% 93.03%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.78% 93.56%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 89.64% 96.47%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 89.23% 95.89%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 88.41% 91.81%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 88.40% 91.24%
CHEMBL2474 P53582 Methionine aminopeptidase 1 88.26% 97.09%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.59% 100.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.94% 94.45%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 86.70% 92.86%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 86.38% 85.94%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.18% 90.71%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 85.78% 94.33%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.51% 90.08%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 85.37% 95.17%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 84.41% 97.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.41% 93.00%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 83.94% 96.25%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.82% 91.11%
CHEMBL3837 P07711 Cathepsin L 83.42% 96.61%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 83.40% 96.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 83.36% 92.88%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 82.76% 98.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.75% 97.09%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.36% 96.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 82.36% 95.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.35% 95.89%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.15% 85.14%
CHEMBL340 P08684 Cytochrome P450 3A4 82.06% 91.19%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 81.88% 91.03%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 80.64% 95.36%
CHEMBL1075317 P61964 WD repeat-containing protein 5 80.55% 96.33%
CHEMBL3055 P50613 Cyclin-dependent kinase 7 80.12% 81.88%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 80.00% 99.23%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6444128
LOTUS LTS0184904
wikiData Q104403521