4-(4,5-Dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-2,7-dihydroxy-3,9-dimethoxy-2,5-dimethyl-3,4-dihydrotetracene-1,6,11-trione

Details

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Internal ID 35f74dea-542f-401e-b5d9-5f4c9a5e891f
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name 4-(4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-2,7-dihydroxy-3,9-dimethoxy-2,5-dimethyl-3,4-dihydrotetracene-1,6,11-trione
SMILES (Canonical) CC1C(C(C(C(O1)OC2C(C(C(=O)C3=CC4=C(C(=C23)C)C(=O)C5=C(C4=O)C=C(C=C5O)OC)(C)O)OC)OC)O)O
SMILES (Isomeric) CC1C(C(C(C(O1)OC2C(C(C(=O)C3=CC4=C(C(=C23)C)C(=O)C5=C(C4=O)C=C(C=C5O)OC)(C)O)OC)OC)O)O
InChI InChI=1S/C29H32O12/c1-10-17-14(21(32)13-7-12(37-4)8-16(30)19(13)22(17)33)9-15-18(10)24(27(39-6)29(3,36)26(15)35)41-28-25(38-5)23(34)20(31)11(2)40-28/h7-9,11,20,23-25,27-28,30-31,34,36H,1-6H3
InChI Key QDSIIYAZDKMMNZ-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C29H32O12
Molecular Weight 572.60 g/mol
Exact Mass 572.18937645 g/mol
Topological Polar Surface Area (TPSA) 178.00 Ų
XlogP 1.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 4-(4,5-Dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-2,7-dihydroxy-3,9-dimethoxy-2,5-dimethyl-3,4-dihydrotetracene-1,6,11-trione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1951 P21397 Monoamine oxidase A 99.04% 91.49%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.55% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.84% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 95.11% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 94.95% 99.23%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 94.72% 99.15%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 94.60% 94.00%
CHEMBL2581 P07339 Cathepsin D 93.48% 98.95%
CHEMBL3714130 P46095 G-protein coupled receptor 6 93.28% 97.36%
CHEMBL4208 P20618 Proteasome component C5 93.20% 90.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 93.12% 92.94%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 92.59% 93.40%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 91.21% 91.07%
CHEMBL3401 O75469 Pregnane X receptor 90.51% 94.73%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 90.32% 96.21%
CHEMBL340 P08684 Cytochrome P450 3A4 86.60% 91.19%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 86.48% 85.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.18% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.48% 95.89%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 83.37% 96.09%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.83% 97.14%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 81.82% 96.38%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.64% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 163057150
LOTUS LTS0124448
wikiData Q105218947