Defumarylhygrolidin

Details

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Internal ID e596325c-6cbb-42ef-b16a-fda0935e1ffc
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (3E,5E,11E,13E)-16-[4-(6-ethyl-2-hydroxy-5-methyloxan-2-yl)-3-hydroxypentan-2-yl]-8-hydroxy-15-methoxy-3,5,7,9,11-pentamethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C34H56O7/c1-11-28-22(4)15-16-34(38,41-28)27(9)31(36)26(8)32-29(39-10)14-12-13-20(2)17-23(5)30(35)24(6)18-21(3)19-25(7)33(37)40-32/h12-14,18-19,22-24,26-32,35-36,38H,11,15-17H2,1-10H3/b14-12+,20-13+,21-18+,25-19+
InChI Key BGFRYHHMLJUGPD-GWYBLXDQSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C34H56O7
Molecular Weight 576.80 g/mol
Exact Mass 576.40260412 g/mol
Topological Polar Surface Area (TPSA) 105.00 Ų
XlogP 6.80

Synonyms

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RefChem:919763
90965-58-5
Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-, (11beta,17beta)-
CHEBI:225013
(3E,5E,11E,13E)-16-[4-(6-ethyl-2-hydroxy-5-methyloxan-2-yl)-3-hydroxypentan-2-yl]-8-hydroxy-15-methoxy-3,5,7,9,11-pentamethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one

2D Structure

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2D Structure of Defumarylhygrolidin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.24% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.53% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.06% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.74% 91.11%
CHEMBL218 P21554 Cannabinoid CB1 receptor 95.53% 96.61%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 93.83% 94.80%
CHEMBL2581 P07339 Cathepsin D 92.40% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.91% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.23% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.05% 94.45%
CHEMBL1902 P62942 FK506-binding protein 1A 88.78% 97.05%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.66% 99.23%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.38% 97.14%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.36% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.27% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 83.82% 92.62%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.34% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.27% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.28% 93.03%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 81.77% 97.33%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 80.14% 86.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589315
LOTUS LTS0028629
wikiData Q104935498