Barakacin

Details

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Internal ID 9d875bd1-5718-47e2-85bb-d802f052f340
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Indoles > 3-alkylindoles
IUPAC Name 2-[4-[bis(1H-indol-3-yl)methyl]-1,3-thiazol-2-yl]phenol
SMILES (Canonical) C1=CC=C2C(=C1)C(=CN2)C(C3=CNC4=CC=CC=C43)C5=CSC(=N5)C6=CC=CC=C6O
SMILES (Isomeric) C1=CC=C2C(=C1)C(=CN2)C(C3=CNC4=CC=CC=C43)C5=CSC(=N5)C6=CC=CC=C6O
InChI InChI=1S/C26H19N3OS/c30-24-12-6-3-9-18(24)26-29-23(15-31-26)25(19-13-27-21-10-4-1-7-16(19)21)20-14-28-22-11-5-2-8-17(20)22/h1-15,25,27-28,30H
InChI Key GRPVXIRSGACTEG-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H19N3OS
Molecular Weight 421.50 g/mol
Exact Mass 421.12488341 g/mol
Topological Polar Surface Area (TPSA) 92.90 Ų
XlogP 5.90

Synonyms

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2-{4-[bis-(1h-indol-3-yl)]-methyl-thiazol-2-yl}-phenol

2D Structure

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2D Structure of Barakacin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.83% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 95.41% 91.49%
CHEMBL213 P08588 Beta-1 adrenergic receptor 95.32% 95.56%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 94.86% 83.10%
CHEMBL2581 P07339 Cathepsin D 93.23% 98.95%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 92.53% 93.03%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 92.42% 99.15%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 90.59% 94.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.41% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.36% 95.56%
CHEMBL1937 Q92769 Histone deacetylase 2 89.26% 94.75%
CHEMBL308 P06493 Cyclin-dependent kinase 1 89.20% 91.73%
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 89.20% 93.24%
CHEMBL2535 P11166 Glucose transporter 88.32% 98.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.17% 94.00%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 85.84% 82.86%
CHEMBL4145 Q9UKV0 Histone deacetylase 9 84.97% 85.49%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 84.07% 96.67%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 83.42% 81.14%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 82.97% 96.47%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 82.77% 83.00%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 82.36% 93.65%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 82.03% 96.39%
CHEMBL3902 P09211 Glutathione S-transferase Pi 81.98% 93.81%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 81.28% 96.09%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 136173294
LOTUS LTS0040040
wikiData Q77512930