4,6,9-trihydroxy-2-methoxy-9-methyl-7-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-8,10-dihydro-7H-tetracene-5,12-dione

Details

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Internal ID dc1f8a55-0f0c-4443-9c8d-0ebd39650224
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name 4,6,9-trihydroxy-2-methoxy-9-methyl-7-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-8,10-dihydro-7H-tetracene-5,12-dione
SMILES (Canonical) CC1C(C(C(C(O1)OC2CC(CC3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=C(C=C5O)OC)(C)O)O)O)O
SMILES (Isomeric) CC1C(C(C(C(O1)OC2CC(CC3=CC4=C(C(=C23)O)C(=O)C5=C(C4=O)C=C(C=C5O)OC)(C)O)O)O)O
InChI InChI=1S/C26H28O11/c1-9-19(28)23(32)24(33)25(36-9)37-15-8-26(2,34)7-10-4-12-18(21(30)16(10)15)22(31)17-13(20(12)29)5-11(35-3)6-14(17)27/h4-6,9,15,19,23-25,27-28,30,32-34H,7-8H2,1-3H3
InChI Key GBILMBMWCHCXLJ-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C26H28O11
Molecular Weight 516.50 g/mol
Exact Mass 516.16316171 g/mol
Topological Polar Surface Area (TPSA) 183.00 Ų
XlogP 0.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of 4,6,9-trihydroxy-2-methoxy-9-methyl-7-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-8,10-dihydro-7H-tetracene-5,12-dione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.79% 91.11%
CHEMBL1951 P21397 Monoamine oxidase A 96.87% 91.49%
CHEMBL1806 P11388 DNA topoisomerase II alpha 96.42% 89.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.80% 96.09%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 95.29% 96.21%
CHEMBL4208 P20618 Proteasome component C5 95.03% 90.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 95.02% 92.94%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.36% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.22% 95.56%
CHEMBL2581 P07339 Cathepsin D 93.90% 98.95%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 93.34% 94.00%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 92.62% 96.38%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 92.13% 99.15%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 92.04% 91.07%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.56% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.62% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.74% 95.89%
CHEMBL226 P30542 Adenosine A1 receptor 87.94% 95.93%
CHEMBL4940 P07195 L-lactate dehydrogenase B chain 87.62% 95.53%
CHEMBL3714130 P46095 G-protein coupled receptor 6 86.96% 97.36%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.82% 97.14%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.48% 96.77%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.57% 97.09%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.11% 95.89%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 81.95% 93.40%
CHEMBL2179 P04062 Beta-glucocerebrosidase 81.56% 85.31%
CHEMBL3714531 Q6P988 Palmitoleoyl-protein carboxylesterase NOTUM 81.15% 97.14%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 80.83% 82.67%
CHEMBL2056 P21728 Dopamine D1 receptor 80.05% 91.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 162912278
LOTUS LTS0166736
wikiData Q104167016