azumamide A

Details

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Internal ID 957e417a-8c6d-48f0-8189-9279917efb0b
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (Z)-6-[(2R,5R,8R,11R,12S)-8-benzyl-5,12-dimethyl-3,6,9,13-tetraoxo-2-propan-2-yl-1,4,7,10-tetrazacyclotridec-11-yl]hex-4-enamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H39N5O5/c1-16(2)23-27(37)29-18(4)25(35)31-21(15-19-11-7-5-8-12-19)26(36)30-20(17(3)24(34)32-23)13-9-6-10-14-22(28)33/h5-9,11-12,16-18,20-21,23H,10,13-15H2,1-4H3,(H2,28,33)(H,29,37)(H,30,36)(H,31,35)(H,32,34)/b9-6-/t17-,18+,20+,21+,23+/m0/s1
InChI Key VADNNPZELPREQB-GIORXHJXSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C27H39N5O5
Molecular Weight 513.60 g/mol
Exact Mass 513.29511936 g/mol
Topological Polar Surface Area (TPSA) 159.00 Ų
XlogP 1.80

Synonyms

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CHEMBL255714
BDBM50377385

2D Structure

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2D Structure of azumamide A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.23% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.71% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.41% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.14% 91.11%
CHEMBL1937 Q92769 Histone deacetylase 2 90.37% 94.75%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.08% 96.47%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.59% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.13% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 88.82% 90.17%
CHEMBL1949 P62937 Cyclophilin A 87.26% 98.57%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.05% 82.69%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 85.62% 97.64%
CHEMBL5103 Q969S8 Histone deacetylase 10 84.57% 90.08%
CHEMBL3060 Q9Y345 Glycine transporter 2 83.54% 99.17%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 83.31% 95.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.62% 86.33%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.14% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.89% 97.09%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 16095102
LOTUS LTS0108268
wikiData Q105282650