Azaspirofuran A, FD 838

Details

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Internal ID c6980624-1201-4bf2-b51f-788c6dc527dd
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Phenylketones > Alkyl-phenylketones
IUPAC Name 8-benzoyl-2-(5-ethylfuran-2-yl)-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H21NO7/c1-4-14-10-11-15(29-14)16-12(2)17(24)21(30-16)19(26)22(28-3,23-20(21)27)18(25)13-8-6-5-7-9-13/h5-11,19,26H,4H2,1-3H3,(H,23,27)
InChI Key PXIIDWGMSCTXAQ-UHFFFAOYSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C22H21NO7
Molecular Weight 411.40 g/mol
Exact Mass 411.13180201 g/mol
Topological Polar Surface Area (TPSA) 115.00 Ų
XlogP 2.30

Synonyms

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110341-78-1
8-benzoyl-2-(5-ethylfuran-2-yl)-9-hydroxy-8-methoxy-3-methyl-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione
BS-1196

2D Structure

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2D Structure of Azaspirofuran A, FD 838

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.54% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.95% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.54% 91.11%
CHEMBL2581 P07339 Cathepsin D 92.98% 98.95%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 92.81% 96.95%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 92.36% 81.11%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.40% 86.33%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.00% 99.23%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.64% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 86.73% 90.17%
CHEMBL4208 P20618 Proteasome component C5 86.32% 90.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.35% 94.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 83.21% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.99% 97.09%
CHEMBL5028 O14672 ADAM10 82.78% 97.50%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 82.69% 97.21%
CHEMBL2535 P11166 Glucose transporter 82.10% 98.75%
CHEMBL3401 O75469 Pregnane X receptor 81.88% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 74966301
LOTUS LTS0126965
wikiData Q105216196