Azalomycin F4a 2-ethylpentyl ester

Details

Top
Internal ID 2e5e809e-822b-4d5a-84d5-ee94ba25cc69
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name 3-O-[(10Z,12Z,18Z,20Z)-3,7,9,23,25,27,31,33,34,35-decahydroxy-10,14,18,22,26,30-hexamethyl-15-[(E)-10-[(N'-methylcarbamimidoyl)amino]dec-6-en-2-yl]-17-oxo-16,37-dioxabicyclo[31.3.1]heptatriaconta-10,12,18,20-tetraen-5-yl] 1-O-(2-ethylpentyl) propanedioate
SMILES (Canonical) CCCC(CC)COC(=O)CC(=O)OC1CC(CC2CC(C(C(O2)(CC(C(CCC(C(C(CC(C(C=CC=C(C(=O)OC(C(C=CC=C(C(CC(C1)O)O)C)C)C(C)CCCC=CCCCNC(=NC)N)C)C)O)O)C)O)C)O)O)O)O)O
SMILES (Isomeric) CCCC(CC)COC(=O)CC(=O)OC1CC(CC2CC(C(C(O2)(CC(C(CCC(C(C(CC(C(/C=C\C=C(/C(=O)OC(C(/C=C\C=C(/C(CC(C1)O)O)\C)C)C(C)CCC/C=C/CCCNC(=NC)N)\C)C)O)O)C)O)C)O)O)O)O)O
InChI InChI=1S/C63H109N3O17/c1-11-21-46(12-2)38-80-57(75)36-58(76)81-49-30-47(67)32-50-34-55(73)60(77)63(79,83-50)37-56(74)41(5)27-28-51(69)45(9)54(72)35-53(71)40(4)24-20-26-44(8)61(78)82-59(43(7)25-19-23-39(3)52(70)33-48(68)31-49)42(6)22-17-15-13-14-16-18-29-66-62(64)65-10/h13-14,19-20,23-26,40-43,45-56,59-60,67-74,77,79H,11-12,15-18,21-22,27-38H2,1-10H3,(H3,64,65,66)/b14-13+,24-20-,25-19-,39-23-,44-26-
InChI Key GHXGVGWREDOHFM-TTZJCZNXSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C63H109N3O17
Molecular Weight 1180.50 g/mol
Exact Mass 1179.77569902 g/mol
Topological Polar Surface Area (TPSA) 341.00 Ų
XlogP 7.20

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Azalomycin F4a 2-ethylpentyl ester

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.66% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.83% 96.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 97.60% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.31% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.24% 95.56%
CHEMBL230 P35354 Cyclooxygenase-2 95.49% 89.63%
CHEMBL261 P00915 Carbonic anhydrase I 94.82% 96.76%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 94.16% 95.71%
CHEMBL2581 P07339 Cathepsin D 94.15% 98.95%
CHEMBL226 P30542 Adenosine A1 receptor 93.81% 95.93%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.45% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.57% 94.45%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 92.34% 96.47%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.27% 99.17%
CHEMBL3401 O75469 Pregnane X receptor 91.52% 94.73%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.33% 99.23%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.10% 95.89%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.38% 100.00%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 89.12% 94.80%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 88.75% 94.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 88.65% 93.56%
CHEMBL340 P08684 Cytochrome P450 3A4 87.14% 91.19%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 87.10% 91.07%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.51% 86.33%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 86.29% 97.21%
CHEMBL4506 Q96EB6 NAD-dependent deacetylase sirtuin 1 86.13% 88.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.23% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.02% 89.00%
CHEMBL299 P17252 Protein kinase C alpha 84.53% 98.03%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.47% 96.00%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 84.26% 94.08%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.25% 96.77%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.22% 96.90%
CHEMBL2514 O95665 Neurotensin receptor 2 83.81% 100.00%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 83.52% 98.75%
CHEMBL5028 O14672 ADAM10 83.25% 97.50%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 82.93% 100.00%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 82.46% 96.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.35% 82.69%
CHEMBL2535 P11166 Glucose transporter 81.60% 98.75%
CHEMBL2072 P35499 Sodium channel protein type IV alpha subunit 81.35% 92.32%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.62% 90.71%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 80.22% 96.95%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 139585016
LOTUS LTS0114835
wikiData Q77380935