Aulacocarpine A

Details

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Internal ID c0ca99df-b814-48ed-867f-bcfd779a9901
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids
IUPAC Name methyl (E)-4-[(1R,2S,4aR,6S,8aS)-6-hydroxy-5,5,8a-trimethylspiro[3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,2'-oxirane]-1-yl]-2-(oxiran-2-yl)but-2-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H32O5/c1-19(2)15-7-10-21(12-26-21)16(20(15,3)9-8-17(19)22)6-5-13(14-11-25-14)18(23)24-4/h5,14-17,22H,6-12H2,1-4H3/b13-5+/t14?,15-,16+,17-,20-,21+/m0/s1
InChI Key DQKIVJKTAXWJRV-LRFKXLDISA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C21H32O5
Molecular Weight 364.50 g/mol
Exact Mass 364.22497412 g/mol
Topological Polar Surface Area (TPSA) 71.60 Ų
XlogP 2.50

Synonyms

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CHEMBL518660

2D Structure

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2D Structure of Aulacocarpine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.03% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.10% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.35% 94.45%
CHEMBL226 P30542 Adenosine A1 receptor 90.45% 95.93%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 90.43% 94.33%
CHEMBL340 P08684 Cytochrome P450 3A4 87.61% 91.19%
CHEMBL1914 P06276 Butyrylcholinesterase 87.58% 95.00%
CHEMBL204 P00734 Thrombin 87.53% 96.01%
CHEMBL3922 P50579 Methionine aminopeptidase 2 86.92% 97.28%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 86.56% 98.75%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 86.16% 82.69%
CHEMBL5028 O14672 ADAM10 86.13% 97.50%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 85.98% 95.50%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.21% 92.62%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.72% 97.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.66% 100.00%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 84.29% 91.24%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.19% 99.23%
CHEMBL2243 O00519 Anandamide amidohydrolase 83.13% 97.53%
CHEMBL4040 P28482 MAP kinase ERK2 83.11% 83.82%
CHEMBL2581 P07339 Cathepsin D 82.94% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 82.75% 90.17%
CHEMBL4227 P25090 Lipoxin A4 receptor 81.56% 100.00%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 81.44% 89.34%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 81.32% 97.47%
CHEMBL253 P34972 Cannabinoid CB2 receptor 81.05% 97.25%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 80.41% 89.05%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.27% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Aframomum aulacocarpos

Cross-Links

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PubChem 44559687
LOTUS LTS0078246
wikiData Q104987000