Astraeusin K epimer

Details

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Internal ID eaea4285-bf96-4e12-b0f0-661b52f7a71f
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Triterpenoids
IUPAC Name (5R,10S,13R,14R,17R)-17-[(1S)-1-[(2S,5R,6S)-6-hydroxy-5-methyloxan-2-yl]ethyl]-4,4,10,13,14-pentamethyl-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H48O3/c1-18-8-10-23(33-26(18)32)19(2)20-12-16-30(7)22-9-11-24-27(3,4)25(31)14-15-28(24,5)21(22)13-17-29(20,30)6/h18-20,23-24,26,32H,8-17H2,1-7H3/t18-,19+,20-,23+,24+,26+,28-,29-,30+/m1/s1
InChI Key HYEBEDUHRUQRHO-VQGVFSKOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C30H48O3
Molecular Weight 456.70 g/mol
Exact Mass 456.36034539 g/mol
Topological Polar Surface Area (TPSA) 46.50 Ų
XlogP 6.80

Synonyms

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(5R,10S,13R,14R,17R)-17-[(1S)-1-[(2S,5R,6S)-6-hydroxy-5-methyloxan-2-yl]ethyl]-4,4,10,13,14-pentamethyl-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
(5R,10S,13R,14R,17R)-17-((1S)-1-((2S,5R,6S)-6-hydroxy-5-methyloxan-2-yl)ethyl)-4,4,10,13,14-pentamethyl-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta(a)phenanthren-3-one
RefChem:115331
CHEBI:200708

2D Structure

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2D Structure of Astraeusin K epimer

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 95.04% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 91.92% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.54% 96.09%
CHEMBL1994 P08235 Mineralocorticoid receptor 86.95% 100.00%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 86.83% 96.38%
CHEMBL1951 P21397 Monoamine oxidase A 86.36% 91.49%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.28% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.95% 99.23%
CHEMBL2842 P42345 Serine/threonine-protein kinase mTOR 85.58% 92.78%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.51% 97.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.85% 86.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 83.82% 96.77%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 82.55% 82.69%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.96% 90.71%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 81.78% 93.04%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.78% 85.14%
CHEMBL2140 P48775 Tryptophan 2,3-dioxygenase 81.30% 98.46%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 80.95% 85.11%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 80.65% 98.33%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139584108
LOTUS LTS0066169
wikiData Q77279775