Asterridinone (ARD)

Details

Top
Internal ID 072b53bc-5805-4436-aa36-c6682844d18d
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > N-alkylindoles
IUPAC Name 3,6-bis[1-(2-methylbut-3-en-2-yl)indol-3-yl]furo[3,2-b]furan-2,5-dione
SMILES (Canonical) CC(C)(C=C)N1C=C(C2=CC=CC=C21)C3=C4C(=C(C(=O)O4)C5=CN(C6=CC=CC=C65)C(C)(C)C=C)OC3=O
SMILES (Isomeric) CC(C)(C=C)N1C=C(C2=CC=CC=C21)C3=C4C(=C(C(=O)O4)C5=CN(C6=CC=CC=C65)C(C)(C)C=C)OC3=O
InChI InChI=1S/C32H28N2O4/c1-7-31(3,4)33-17-21(19-13-9-11-15-23(19)33)25-27-28(38-29(25)35)26(30(36)37-27)22-18-34(32(5,6)8-2)24-16-12-10-14-20(22)24/h7-18H,1-2H2,3-6H3
InChI Key IRJGMAFRZLADJC-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C32H28N2O4
Molecular Weight 504.60 g/mol
Exact Mass 504.20490738 g/mol
Topological Polar Surface Area (TPSA) 62.50 Ų
XlogP 5.80

Synonyms

Top
NSC676675
Asterridinone
CHEMBL1971765
NSC-676675
3,6-Bis(1-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl)furo[3,2-b]furan-2,5-dione
NCI60_027162
3,6-bis[1-(1,1-dimethylallyl)indol-3-yl]furo[3,2-b]furan-2,5-dione

2D Structure

Top
2D Structure of Asterridinone (ARD)

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 98.43% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 97.15% 91.49%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 96.12% 93.65%
CHEMBL2581 P07339 Cathepsin D 94.95% 98.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.84% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.56% 86.33%
CHEMBL3401 O75469 Pregnane X receptor 90.98% 94.73%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.89% 89.00%
CHEMBL230 P35354 Cyclooxygenase-2 87.31% 89.63%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 83.44% 90.93%
CHEMBL5805 Q9NR97 Toll-like receptor 8 81.77% 96.25%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 81.37% 94.62%
CHEMBL1868 P17948 Vascular endothelial growth factor receptor 1 80.99% 96.47%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 80.31% 80.78%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 385440
LOTUS LTS0036124
wikiData Q77514113