Aspochalasin L

Details

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Internal ID e9806555-fce4-4498-a6c3-eb8b829f312c
Taxonomy Alkaloids and derivatives > Cytochalasans > Aspochalasins
IUPAC Name (1R,9E,11R,12R,15R,16S)-5,6,12-trihydroxy-4-methoxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-9,13-diene-2,18-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C25H39NO6/c1-12(2)9-17-21-14(4)15(5)22(29)16-10-13(3)7-8-18(27)23(30)19(32-6)11-20(28)25(16,21)24(31)26-17/h10,12,16-19,21-23,27,29-30H,7-9,11H2,1-6H3,(H,26,31)/b13-10+/t16-,17-,18?,19?,21-,22-,23?,25+/m0/s1
InChI Key SEJALNVFDONJGO-GXVMMTHKSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C25H39NO6
Molecular Weight 449.60 g/mol
Exact Mass 449.27773796 g/mol
Topological Polar Surface Area (TPSA) 116.00 Ų
XlogP 0.40

Synonyms

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SV5K9D2538
861136-81-4
(1R,9E,11R,12R,15R,16S)-5,6,12-Trihydroxy-4-methoxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo[9.7.0.01,15]octadeca-9,13-diene-2,18-dione
(1R,9E,11R,12R,15R,16S)-5,6,12-trihydroxy-4-methoxy-9,13,14-trimethyl-16-(2-methylpropyl)-17-azatricyclo(9.7.0.01,15)octadeca-9,13-diene-2,18-dione
RefChem:115198
UNII-SV5K9D2538
1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,6,6a,9,10,11,12,13,14-decahydro-6,11,12-trihydroxy-13-methoxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,6R,6aR,7E,15aR)-
CHEBI:211676

2D Structure

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2D Structure of Aspochalasin L

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.13% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.21% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.40% 91.11%
CHEMBL204 P00734 Thrombin 94.27% 96.01%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.95% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.18% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.93% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.07% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.95% 97.09%
CHEMBL1937 Q92769 Histone deacetylase 2 88.08% 94.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 87.64% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.43% 95.89%
CHEMBL2535 P11166 Glucose transporter 87.07% 98.75%
CHEMBL2996 Q05655 Protein kinase C delta 86.42% 97.79%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.13% 90.71%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.48% 93.03%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 84.20% 92.88%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.98% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.90% 99.23%
CHEMBL1902 P62942 FK506-binding protein 1A 80.73% 97.05%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.61% 93.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11396751
LOTUS LTS0080693
wikiData Q77493525