Asperindole A

Details

Top
Internal ID 30b1b46a-6076-4dc2-a590-f00ea1d14348
Taxonomy Organoheterocyclic compounds > Naphthopyrans
IUPAC Name [(1R,4R,5S,16S,19S,23R,24S)-10-chloro-19-hydroxy-4,5,24-trimethyl-22-oxo-26,27-dioxa-7-azaheptacyclo[21.3.1.01,20.04,19.05,16.06,14.08,13]heptacosa-6(14),8(13),9,11,20-pentaen-24-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H32ClNO6/c1-15(32)36-25(2)14-35-29-10-9-26(3)27(4)16(7-8-28(26,34)22(29)13-21(33)24(25)37-29)11-19-18-6-5-17(30)12-20(18)31-23(19)27/h5-6,12-13,16,24,31,34H,7-11,14H2,1-4H3/t16-,24-,25-,26+,27+,28+,29+/m0/s1
InChI Key TXNJCXRRMWHWPI-VZTTULSBSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C29H32ClNO6
Molecular Weight 526.00 g/mol
Exact Mass 525.1918154 g/mol
Topological Polar Surface Area (TPSA) 97.90 Ų
XlogP 3.30

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Asperindole A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 99.92% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.72% 91.11%
CHEMBL2581 P07339 Cathepsin D 95.06% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.40% 96.09%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 94.17% 94.62%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 94.09% 94.80%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.58% 93.40%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 93.52% 94.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.53% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.88% 97.09%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 89.71% 89.05%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.26% 94.00%
CHEMBL340 P08684 Cytochrome P450 3A4 89.07% 91.19%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.05% 89.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 87.77% 85.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 87.70% 96.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.98% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.65% 86.33%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.34% 100.00%
CHEMBL255 P29275 Adenosine A2b receptor 86.03% 98.59%
CHEMBL2039 P27338 Monoamine oxidase B 85.64% 92.51%
CHEMBL1937 Q92769 Histone deacetylase 2 85.40% 94.75%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.09% 92.62%
CHEMBL3922 P50579 Methionine aminopeptidase 2 85.09% 97.28%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.08% 100.00%
CHEMBL217 P14416 Dopamine D2 receptor 84.41% 95.62%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 84.36% 94.08%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 83.99% 95.78%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.29% 95.50%
CHEMBL241 Q14432 Phosphodiesterase 3A 81.02% 92.94%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 80.71% 85.94%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 80.48% 92.88%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 139590649
LOTUS LTS0125258
wikiData Q105266864