Aspergillide D

Details

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Internal ID 0c8d0930-220c-4db7-ae33-ab5ba5843f75
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (3S,6R,9S,12S,15S)-6-[(4-hydroxyphenyl)methyl]-9,12-bis[(4-methoxyphenyl)methyl]-7-methyl-3-propan-2-yl-1,4,7,10,13-pentazabicyclo[13.3.0]octadecane-2,5,8,11,14-pentone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H49N5O8/c1-24(2)35-40(51)45-20-6-7-33(45)37(48)41-31(21-25-10-16-29(52-4)17-11-25)36(47)42-32(22-26-12-18-30(53-5)19-13-26)39(50)44(3)34(38(49)43-35)23-27-8-14-28(46)15-9-27/h8-19,24,31-35,46H,6-7,20-23H2,1-5H3,(H,41,48)(H,42,47)(H,43,49)/t31-,32-,33-,34+,35-/m0/s1
InChI Key GXJNHGQMYBROHH-ISWDJSIVSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C40H49N5O8
Molecular Weight 727.80 g/mol
Exact Mass 727.35811354 g/mol
Topological Polar Surface Area (TPSA) 167.00 Ų
XlogP 4.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Aspergillide D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.69% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.21% 96.09%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.80% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.48% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 96.19% 95.89%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.90% 95.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 95.48% 90.08%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.03% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.95% 91.11%
CHEMBL4208 P20618 Proteasome component C5 92.36% 90.00%
CHEMBL226 P30542 Adenosine A1 receptor 91.49% 95.93%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.05% 95.89%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.49% 99.15%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 90.45% 82.38%
CHEMBL5203 P33316 dUTP pyrophosphatase 89.93% 99.18%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.21% 97.25%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.31% 94.00%
CHEMBL1902 P62942 FK506-binding protein 1A 87.39% 97.05%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.26% 93.00%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 85.65% 96.69%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 84.35% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.16% 90.71%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 82.06% 93.40%
CHEMBL4616 Q92847 Ghrelin receptor 81.51% 92.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 81.32% 97.64%
CHEMBL2535 P11166 Glucose transporter 81.31% 98.75%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 80.80% 85.00%
CHEMBL3524 P56524 Histone deacetylase 4 80.45% 92.97%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132496356
LOTUS LTS0083608
wikiData Q105023106