Asperdiazapinone A

Details

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Internal ID 67d9ed11-39d2-4e61-8c14-2be9e9aa7b05
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyrroloindoles
IUPAC Name (2S,10R,12S)-6-methoxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4(9),5,7,15,17,19-hexaene-13,21-dione
SMILES (Canonical) CC(C)(C=C)C12CC3C(=O)NC4=CC=CC=C4C(=O)N3C1NC5=C2C=CC(=C5)OC
SMILES (Isomeric) CC(C)(C=C)[C@@]12C[C@H]3C(=O)NC4=CC=CC=C4C(=O)N3[C@@H]1NC5=C2C=CC(=C5)OC
InChI InChI=1S/C24H25N3O3/c1-5-23(2,3)24-13-19-20(28)25-17-9-7-6-8-15(17)21(29)27(19)22(24)26-18-12-14(30-4)10-11-16(18)24/h5-12,19,22,26H,1,13H2,2-4H3,(H,25,28)/t19-,22-,24+/m0/s1
InChI Key FCEVLFGWAZSGTN-NGYIFUPDSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C24H25N3O3
Molecular Weight 403.50 g/mol
Exact Mass 403.18959167 g/mol
Topological Polar Surface Area (TPSA) 70.70 Ų
XlogP 4.20

Synonyms

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CHEBI:188678
(2S,10R,12S)-6-methoxy-10-(2-methylbut-3-en-2-yl)-1,3,14-triazapentacyclo[10.9.0.02,10.04,9.015,20]henicosa-4(9),5,7,15,17,19-hexaene-13,21-dione

2D Structure

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2D Structure of Asperdiazapinone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.96% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 97.20% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.95% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.61% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 94.56% 93.40%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 94.08% 82.69%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.05% 86.33%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 91.91% 97.14%
CHEMBL1951 P21397 Monoamine oxidase A 90.82% 91.49%
CHEMBL4208 P20618 Proteasome component C5 90.59% 90.00%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 88.82% 92.67%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.69% 97.09%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 87.78% 80.78%
CHEMBL1907 P15144 Aminopeptidase N 87.37% 93.31%
CHEMBL1902 P62942 FK506-binding protein 1A 86.43% 97.05%
CHEMBL2535 P11166 Glucose transporter 86.40% 98.75%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.06% 97.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.87% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.05% 99.23%
CHEMBL4531 P17931 Galectin-3 82.84% 96.90%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 82.46% 91.07%
CHEMBL226 P30542 Adenosine A1 receptor 82.17% 95.93%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.16% 93.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 102228309
LOTUS LTS0102002
wikiData Q77382672