Ascospiroketal A

Details

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Internal ID 9ec602cc-02b3-498d-8f42-e70e6d110a56
Taxonomy Organoheterocyclic compounds > Furofurans
IUPAC Name (3S,3aS,5S,5'R,6aS)-5'-[(1E,3Z)-6-(3-hydroxy-2-methylbutanoyl)oxyhepta-1,3-dienyl]-3-methylspiro[2,3a,6,6a-tetrahydrofuro[3,2-b]furan-5,2'-oxolane]-3-carboxylic acid
SMILES (Canonical) CC(CC=CC=CC1CCC2(O1)CC3C(O2)C(CO3)(C)C(=O)O)OC(=O)C(C)C(C)O
SMILES (Isomeric) CC(C/C=C\C=C\[C@H]1CC[C@@]2(O1)C[C@H]3[C@@H](O2)[C@@](CO3)(C)C(=O)O)OC(=O)C(C)C(C)O
InChI InChI=1S/C23H34O8/c1-14(29-20(25)15(2)16(3)24)8-6-5-7-9-17-10-11-23(30-17)12-18-19(31-23)22(4,13-28-18)21(26)27/h5-7,9,14-19,24H,8,10-13H2,1-4H3,(H,26,27)/b6-5-,9-7+/t14?,15?,16?,17-,18-,19+,22-,23-/m0/s1
InChI Key HITJIMVQWUIHFQ-YFDCLKMTSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C23H34O8
Molecular Weight 438.50 g/mol
Exact Mass 438.22536804 g/mol
Topological Polar Surface Area (TPSA) 112.00 Ų
XlogP 2.20

Synonyms

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(3S,3aS,5S,5'R,6aS)-5'-[(1E,3Z)-6-(3-hydroxy-2-methylbutanoyl)oxyhepta-1,3-dienyl]-3-methylspiro[2,3a,6,6a-tetrahydrofuro[3,2-b]furan-5,2'-oxolane]-3-carboxylic acid

2D Structure

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2D Structure of Ascospiroketal A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.71% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.77% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.43% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.44% 97.09%
CHEMBL221 P23219 Cyclooxygenase-1 93.13% 90.17%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.82% 96.47%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 87.67% 98.75%
CHEMBL2179 P04062 Beta-glucocerebrosidase 87.61% 85.31%
CHEMBL218 P21554 Cannabinoid CB1 receptor 85.19% 96.61%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.14% 92.62%
CHEMBL204 P00734 Thrombin 83.92% 96.01%
CHEMBL268 P43235 Cathepsin K 82.43% 96.85%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 82.06% 89.05%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 81.91% 91.07%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.28% 95.56%
CHEMBL236 P41143 Delta opioid receptor 81.21% 99.35%
CHEMBL4227 P25090 Lipoxin A4 receptor 81.10% 100.00%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 80.35% 97.47%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 80.28% 95.17%
CHEMBL2413 P32246 C-C chemokine receptor type 1 80.22% 89.50%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.12% 95.89%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.06% 99.17%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.01% 89.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 22833222
LOTUS LTS0054727
wikiData Q75062641