Arthrichitin

Details

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Internal ID 76e6d63b-4973-4d04-8458-edea8173d65f
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 3-[(3S,6S,9R,12S,13S)-13-[(2R)-decan-2-yl]-3-(hydroxymethyl)-6-(1H-indole-3-carbonyl)-12-methyl-2,5,8,11-tetraoxo-1-oxa-4,7,10-triazacyclotridec-9-yl]propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C33H46N4O9/c1-4-5-6-7-8-9-12-19(2)29-20(3)30(42)35-24(15-16-26(39)40)31(43)37-27(32(44)36-25(18-38)33(45)46-29)28(41)22-17-34-23-14-11-10-13-21(22)23/h10-11,13-14,17,19-20,24-25,27,29,34,38H,4-9,12,15-16,18H2,1-3H3,(H,35,42)(H,36,44)(H,37,43)(H,39,40)/t19-,20+,24-,25+,27+,29+/m1/s1
InChI Key VNRAPWIEXZLTKI-ZDSZPENHSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C33H46N4O9
Molecular Weight 642.70 g/mol
Exact Mass 642.32647906 g/mol
Topological Polar Surface Area (TPSA) 204.00 Ų
XlogP 5.00

Synonyms

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180462-26-4
Cyclo(3-hydroxy-2,4-dimethyldodecanoyl-L-alpha-glutamyl-beta-oxotryptophyl-L-seryl)
DTXSID50170964
Cyclo(3-hydroxy-2,4-dimethyldodecanoyl-L-.alpha.-glutamyl-.beta.- oxotryptophyl-L-seryl)
3-[(3S,6S,9R,12S,13S)-3-(hydroxymethyl)-6-(1H-indole-3-carbonyl)-12-methyl-13-[(1R)-1-methylnonyl]-2,5,8,11-tetraoxo-1-oxa-4,7,10-triazacyclotridec-9-yl]propanoic acid

2D Structure

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2D Structure of Arthrichitin

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.40% 98.95%
CHEMBL2996 Q05655 Protein kinase C delta 97.34% 97.79%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.88% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.62% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.26% 91.11%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 94.70% 91.81%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.95% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.89% 99.17%
CHEMBL3310 Q96DB2 Histone deacetylase 11 91.36% 88.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.26% 99.23%
CHEMBL5103 Q969S8 Histone deacetylase 10 91.09% 90.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.98% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 90.70% 90.17%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 90.52% 97.64%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 90.15% 96.47%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 90.06% 92.08%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.67% 93.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.77% 89.00%
CHEMBL299 P17252 Protein kinase C alpha 86.77% 98.03%
CHEMBL5285 Q99683 Mitogen-activated protein kinase kinase kinase 5 84.85% 92.26%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.18% 96.90%
CHEMBL230 P35354 Cyclooxygenase-2 83.81% 89.63%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 83.78% 94.62%
CHEMBL1781 P11387 DNA topoisomerase I 82.67% 97.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.44% 100.00%
CHEMBL3004 P33527 Multidrug resistance-associated protein 1 81.81% 96.37%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 80.21% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 492215
LOTUS LTS0130755
wikiData Q83040985