Arctignan D

Details

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Internal ID d5bc62b9-fdcd-4a61-8e00-f07fee2e1f86
Taxonomy Phenylpropanoids and polyketides > 2-arylbenzofuran flavonoids
IUPAC Name (3R,4R)-4-[[3-[1,3-dihydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-2-yl]-4-hydroxy-5-methoxyphenyl]methyl]-3-[[(2S,3R)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-2,3-dihydro-1-benzofuran-5-yl]methyl]oxolan-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H44O13/c1-48-32-15-22(5-7-30(32)43)36(45)28(17-41)26-11-20(13-34(50-3)37(26)46)9-24-19-52-40(47)25(24)10-21-12-27-29(18-42)38(53-39(27)35(14-21)51-4)23-6-8-31(44)33(16-23)49-2/h5-8,11-16,24-25,28-29,36,38,41-46H,9-10,17-19H2,1-4H3/t24-,25+,28?,29-,36?,38+/m0/s1
InChI Key YUHXLTKARLJXBV-FGEPHIOBSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C40H44O13
Molecular Weight 732.80 g/mol
Exact Mass 732.27819145 g/mol
Topological Polar Surface Area (TPSA) 194.00 Ų
XlogP 3.70

Synonyms

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UNII-Q85JI2VL1N
Q85JI2VL1N
155661-11-3
2(3H)-Furanone, 3-((2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-7-methoxy-5-benzofuranyl)methyl)dihydro-4-((4-hydroxy-3-(2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethyl)-5-methoxyphenyl)methyl)-
Q27287104

2D Structure

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2D Structure of Arctignan D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 99.30% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.98% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.97% 91.11%
CHEMBL2581 P07339 Cathepsin D 97.51% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.07% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.93% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.35% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 93.29% 92.62%
CHEMBL204 P00734 Thrombin 92.97% 96.01%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 90.06% 99.15%
CHEMBL3060 Q9Y345 Glycine transporter 2 89.48% 99.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.51% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.33% 95.89%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 86.97% 95.89%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 86.15% 97.14%
CHEMBL3401 O75469 Pregnane X receptor 85.16% 94.73%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 82.74% 86.92%
CHEMBL1978 P11511 Cytochrome P450 19A1 82.73% 91.76%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 82.37% 96.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.23% 89.00%
CHEMBL2535 P11166 Glucose transporter 80.80% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Arctium lappa

Cross-Links

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PubChem 73425493
LOTUS LTS0071802
wikiData Q27287104