Aqabamycin G

Details

Top
Internal ID 52dab696-985c-4de3-9c48-a4455a16afe3
Taxonomy Benzenoids > Phenols > Nitrophenols
IUPAC Name 3-(4-hydroxy-3-nitrophenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione
SMILES (Canonical) C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CC(=C(C=C4)O)[N+](=O)[O-]
SMILES (Isomeric) C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CC(=C(C=C4)O)[N+](=O)[O-]
InChI InChI=1S/C18H11N3O5/c22-14-6-5-9(7-13(14)21(25)26)15-16(18(24)20-17(15)23)11-8-19-12-4-2-1-3-10(11)12/h1-8,19,22H,(H,20,23,24)
InChI Key LSXYUYXMNIJERR-UHFFFAOYSA-N
Popularity 4 references in papers

Physical and Chemical Properties

Top
Molecular Formula C18H11N3O5
Molecular Weight 349.30 g/mol
Exact Mass 349.06987046 g/mol
Topological Polar Surface Area (TPSA) 128.00 Ų
XlogP 2.70

Synonyms

Top
1252019-82-1
3-(4-hydroxy-3-nitrophenyl)-4-(1H-indol-3-yl)pyrrole-2,5-dione
CHEMBL4278551

2D Structure

Top
2D Structure of Aqabamycin G

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1951 P21397 Monoamine oxidase A 98.23% 91.49%
CHEMBL262 P49841 Glycogen synthase kinase-3 beta 98.04% 95.72%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.73% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.25% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.32% 95.56%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 95.07% 92.88%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 94.96% 88.84%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.85% 89.00%
CHEMBL4225 P49760 Dual specificity protein kinase CLK2 93.34% 80.96%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 90.82% 83.10%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 90.75% 94.62%
CHEMBL3038469 P24941 CDK2/Cyclin A 90.22% 91.38%
CHEMBL2535 P11166 Glucose transporter 89.96% 98.75%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.78% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 89.35% 93.03%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 88.86% 93.40%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 88.58% 99.15%
CHEMBL3902 P09211 Glutathione S-transferase Pi 86.40% 93.81%
CHEMBL2708 Q16584 Mitogen-activated protein kinase kinase kinase 11 85.92% 81.14%
CHEMBL2996 Q05655 Protein kinase C delta 85.22% 97.79%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.94% 99.23%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 84.90% 92.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.60% 94.45%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 84.33% 91.71%
CHEMBL3045 P05771 Protein kinase C beta 83.87% 97.63%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.42% 94.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 81.82% 95.56%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 81.10% 95.71%
CHEMBL221 P23219 Cyclooxygenase-1 80.67% 90.17%
CHEMBL240 Q12809 HERG 80.64% 89.76%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 80.58% 100.00%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 46846124
LOTUS LTS0092964
wikiData Q77569940