Aplysinone D

Details

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Internal ID 755ca975-b43b-4156-9fae-70ac03165e35
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Cyclic ketones > Cyclohexenones
IUPAC Name (5S,6R)-7,9-dibromo-N-[4-[[(5S,6R,7S)-7,9-dibromo-6-hydroxy-8-oxo-1-oxa-2-azaspiro[4.5]deca-2,9-diene-3-carbonyl]amino]butyl]-6-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,7,9-triene-3-carboxamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H24Br4N4O8/c1-37-17-11(25)7-23(19(34)15(17)27)9-13(31-39-23)21(36)29-5-3-2-4-28-20(35)12-8-22(38-30-12)6-10(24)16(32)14(26)18(22)33/h6-7,14,18-19,33-34H,2-5,8-9H2,1H3,(H,28,35)(H,29,36)/t14-,18+,19+,22-,23-/m1/s1
InChI Key ONDRQQMSEBCZNC-JFCOBKCCSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C23H24Br4N4O8
Molecular Weight 804.10 g/mol
Exact Mass 803.82867 g/mol
Topological Polar Surface Area (TPSA) 168.00 Ų
XlogP 1.10

Synonyms

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(5S,6R)-7,9-dibromo-N-(4-(((5S,6R,7S)-7,9-dibromo-6-hydroxy-8-oxo-1-oxa-2-azaspiro(4.5)deca-2,9-diene-3-carbonyl)amino)butyl)-6-hydroxy-8-methoxy-1-oxa-2-azaspiro(4.5)deca-2,7,9-triene-3-carboxamide
(5S,6R)-7,9-dibromo-N-[4-[[(5S,6R,7S)-7,9-dibromo-6-hydroxy-8-oxo-1-oxa-2-azaspiro[4.5]deca-2,9-diene-3-carbonyl]amino]butyl]-6-hydroxy-8-methoxy-1-oxa-2-azaspiro[4.5]deca-2,7,9-triene-3-carboxamide
RefChem:113459
CHEMBL425659

2D Structure

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2D Structure of Aplysinone D

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.64% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.59% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.68% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.97% 94.45%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.29% 95.56%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 91.16% 94.00%
CHEMBL221 P23219 Cyclooxygenase-1 87.36% 90.17%
CHEMBL3401 O75469 Pregnane X receptor 87.20% 94.73%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.35% 99.23%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 85.31% 91.07%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.13% 99.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.49% 86.33%
CHEMBL240 Q12809 HERG 82.45% 89.76%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 82.33% 91.24%
CHEMBL5028 O14672 ADAM10 80.69% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44424475
LOTUS LTS0092771
wikiData Q105194607