Aphidicolin A66

Details

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Internal ID 16f41f1f-aff3-471f-bf73-bd1a5f68880d
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Aphidicolane and stemodane diterpenoids
IUPAC Name (1R,2S,6S,7S,11R,12S,13R)-11,13-dihydroxy-13-(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.01,10.02,7]hexadec-9-en-5-one
SMILES (Canonical) CC1C2CC=C3C(C4CC3(C2(CCC1=O)C)CCC4(CO)O)O
SMILES (Isomeric) C[C@H]1[C@@H]2CC=C3[C@@H]([C@@H]4C[C@@]3([C@]2(CCC1=O)C)CC[C@@]4(CO)O)O
InChI InChI=1S/C19H28O4/c1-11-12-3-4-13-16(22)14-9-18(13,7-8-19(14,23)10-20)17(12,2)6-5-15(11)21/h4,11-12,14,16,20,22-23H,3,5-10H2,1-2H3/t11-,12-,14-,16-,17-,18-,19-/m0/s1
InChI Key LNZYJSLTBFBUBA-OQCIHVHGSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C19H28O4
Molecular Weight 320.40 g/mol
Exact Mass 320.19875937 g/mol
Topological Polar Surface Area (TPSA) 77.80 Ų
XlogP 0.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Aphidicolin A66

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.99% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.27% 91.11%
CHEMBL226 P30542 Adenosine A1 receptor 94.87% 95.93%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.54% 97.25%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.76% 95.56%
CHEMBL2581 P07339 Cathepsin D 89.59% 98.95%
CHEMBL1994 P08235 Mineralocorticoid receptor 87.93% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.55% 97.09%
CHEMBL1293249 Q13887 Kruppel-like factor 5 85.50% 86.33%
CHEMBL4040 P28482 MAP kinase ERK2 84.68% 83.82%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 84.47% 96.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.17% 96.77%
CHEMBL221 P23219 Cyclooxygenase-1 83.64% 90.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 81.44% 85.14%
CHEMBL4208 P20618 Proteasome component C5 81.07% 90.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 145721159
LOTUS LTS0134747
wikiData Q105154597