Aphidicolin A31

Details

Top
Internal ID ec690e5e-f6c7-4f92-a26a-918d223e3646
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Aphidicolane and stemodane diterpenoids
IUPAC Name [(1R,2S,5R,6R,7R,9S,12S,13R)-5,9,13-trihydroxy-6-(hydroxymethyl)-2,6-dimethyl-13-tetracyclo[10.3.1.01,10.02,7]hexadec-10-enyl]methyl acetate
SMILES (Canonical) CC(=O)OCC1(CCC23CC1C=C2C(CC4C3(CCC(C4(C)CO)O)C)O)O
SMILES (Isomeric) CC(=O)OC[C@]1(CC[C@]23C[C@H]1C=C2[C@H](C[C@@H]4[C@@]3(CC[C@H]([C@@]4(C)CO)O)C)O)O
InChI InChI=1S/C22H34O6/c1-13(24)28-12-22(27)7-6-21-10-14(22)8-15(21)16(25)9-17-19(2,11-23)18(26)4-5-20(17,21)3/h8,14,16-18,23,25-27H,4-7,9-12H2,1-3H3/t14-,16+,17+,18-,19+,20+,21+,22+/m1/s1
InChI Key FZJYRVLKMJUXDU-PHHBAXLXSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

Top
Molecular Formula C22H34O6
Molecular Weight 394.50 g/mol
Exact Mass 394.23553880 g/mol
Topological Polar Surface Area (TPSA) 107.00 Ų
XlogP 1.00

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Aphidicolin A31

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.96% 96.09%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 93.71% 82.69%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.87% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.49% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.98% 94.45%
CHEMBL1994 P08235 Mineralocorticoid receptor 89.86% 100.00%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.33% 96.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 88.50% 97.25%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 88.04% 95.50%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.51% 95.56%
CHEMBL221 P23219 Cyclooxygenase-1 86.00% 90.17%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.85% 94.33%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.93% 86.33%
CHEMBL2581 P07339 Cathepsin D 83.26% 98.95%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.77% 95.89%
CHEMBL5028 O14672 ADAM10 82.19% 97.50%
CHEMBL241 Q14432 Phosphodiesterase 3A 81.08% 92.94%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 145721122
LOTUS LTS0190317
wikiData Q105004982