Aphidicolin A2

Details

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Internal ID a9985764-c059-4fab-a98c-c9b79143bd0f
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Oxasteroids and derivatives
IUPAC Name [(1S,2S,5R,10R,11R,14S,16R,17R)-17-hydroxy-2,7,7,10-tetramethyl-6,8-dioxapentacyclo[14.3.1.01,14.02,11.05,10]icosan-17-yl]methyl acetate
SMILES (Canonical) CC(=O)OCC1(CCC23CC1CC2CCC4C3(CCC5C4(COC(O5)(C)C)C)C)O
SMILES (Isomeric) CC(=O)OC[C@]1(CC[C@]23C[C@H]1C[C@@H]2CC[C@@H]4[C@@]3(CC[C@@H]5[C@]4(COC(O5)(C)C)C)C)O
InChI InChI=1S/C25H40O5/c1-16(26)28-15-25(27)11-10-24-13-18(25)12-17(24)6-7-19-22(4)14-29-21(2,3)30-20(22)8-9-23(19,24)5/h17-20,27H,6-15H2,1-5H3/t17-,18+,19-,20+,22-,23-,24-,25-/m0/s1
InChI Key WTLPSBZUQMYRGQ-WEXNTJFTSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C25H40O5
Molecular Weight 420.60 g/mol
Exact Mass 420.28757437 g/mol
Topological Polar Surface Area (TPSA) 65.00 Ų
XlogP 4.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Aphidicolin A2

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.80% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.61% 96.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 96.64% 97.25%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.82% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.69% 97.09%
CHEMBL340 P08684 Cytochrome P450 3A4 91.91% 91.19%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 91.03% 96.95%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 89.46% 82.69%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 87.16% 94.62%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 87.12% 95.50%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.03% 92.62%
CHEMBL1914 P06276 Butyrylcholinesterase 86.19% 95.00%
CHEMBL240 Q12809 HERG 86.09% 89.76%
CHEMBL3922 P50579 Methionine aminopeptidase 2 86.07% 97.28%
CHEMBL3437 Q16853 Amine oxidase, copper containing 86.03% 94.00%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 85.39% 95.71%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.35% 100.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.78% 97.14%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 81.62% 89.05%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 81.19% 96.77%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.76% 89.00%
CHEMBL2782 P35610 Acyl coenzyme A:cholesterol acyltransferase 1 80.50% 91.65%
CHEMBL1951 P21397 Monoamine oxidase A 80.31% 91.49%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 145721120
LOTUS LTS0223803
wikiData Q105312638