Ansalactam B

Details

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Internal ID c3e87d49-93d0-4313-8c04-6fe3565c6cf2
Taxonomy Benzenoids > Naphthalenes > Naphthoquinones
IUPAC Name (1R,4R,5R,6R,7S,8E,10R,11Z,13E,23S)-7,17-dihydroxy-6,8,10,12,14,18-hexamethyl-4-(2-methylpropyl)-2-azapentacyclo[18.3.1.01,5.07,23.016,21]tetracosa-8,11,13,16,18,20-hexaene-3,15,22,24-tetrone
SMILES (Canonical) CC1C=C(C=C(C(=O)C2=C(C(=CC3=C2C(=O)C4C(C(C5C4(C3=O)NC(=O)C5CC(C)C)C)(C(=C1)C)O)C)O)C)C
SMILES (Isomeric) C[C@@H]\1/C=C(\C=C(\C(=O)C2=C(C(=CC3=C2C(=O)[C@@H]4[C@@]([C@@H]([C@H]5[C@@]4(C3=O)NC(=O)[C@@H]5CC(C)C)C)(/C(=C1)/C)O)C)O)/C)/C
InChI InChI=1S/C33H39NO6/c1-14(2)9-22-25-20(8)33(40)19(7)12-16(4)10-15(3)11-17(5)26(35)24-23-21(13-18(6)27(24)36)30(38)32(25,34-31(22)39)29(33)28(23)37/h10-14,16,20,22,25,29,36,40H,9H2,1-8H3,(H,34,39)/b15-10-,17-11+,19-12+/t16-,20-,22-,25-,29+,32-,33+/m1/s1
InChI Key XYLCRXBLUITNGR-MWVWETOZSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C33H39NO6
Molecular Weight 545.70 g/mol
Exact Mass 545.27773796 g/mol
Topological Polar Surface Area (TPSA) 121.00 Ų
XlogP 4.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Ansalactam B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.40% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.02% 91.11%
CHEMBL1937 Q92769 Histone deacetylase 2 96.97% 94.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 95.15% 89.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.17% 95.56%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.74% 85.14%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 91.18% 93.40%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 90.72% 90.71%
CHEMBL226 P30542 Adenosine A1 receptor 89.32% 95.93%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 88.08% 96.90%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 88.06% 85.11%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 87.51% 89.67%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 81.59% 97.21%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.54% 95.89%
CHEMBL4581 P52732 Kinesin-like protein 1 81.50% 93.18%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.46% 99.23%
CHEMBL4530 P00488 Coagulation factor XIII 81.38% 96.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.27% 93.03%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 80.98% 96.77%
CHEMBL4208 P20618 Proteasome component C5 80.79% 90.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 80.66% 95.89%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.20% 100.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.05% 90.08%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 80.05% 86.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132560772
LOTUS LTS0060577
wikiData Q77369858