Amidepsine I

Details

Top
Internal ID 57598520-63fe-4c71-89cb-4e3ddcf7c13a
Taxonomy Phenylpropanoids and polyketides > Tannins > Hydrolyzable tannins
IUPAC Name (2S)-2-[[4-[2-[(2S,3R,4S,5S,6R)-3-acetyloxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-(2-hydroxy-4-methoxy-6-methylbenzoyl)oxy-6-methylbenzoyl]oxy-2-hydroxy-6-methylbenzoyl]amino]propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C36H39NO17/c1-14-8-20(11-22(40)26(14)32(44)37-17(4)33(45)46)51-35(48)28-16(3)9-21(52-34(47)27-15(2)7-19(49-6)10-23(27)41)12-24(28)53-36-31(50-18(5)39)30(43)29(42)25(13-38)54-36/h7-12,17,25,29-31,36,38,40-43H,13H2,1-6H3,(H,37,44)(H,45,46)/t17-,25+,29+,30-,31+,36+/m0/s1
InChI Key RBFOMTAWEHHDSX-SBCZIEDESA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C36H39NO17
Molecular Weight 757.70 g/mol
Exact Mass 757.22179878 g/mol
Topological Polar Surface Area (TPSA) 274.00 Ų
XlogP 3.90

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Amidepsine I

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.05% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.29% 96.09%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 95.35% 99.15%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.71% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 92.97% 99.17%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 92.59% 96.00%
CHEMBL3401 O75469 Pregnane X receptor 91.97% 94.73%
CHEMBL2581 P07339 Cathepsin D 91.79% 98.95%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.09% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.31% 91.07%
CHEMBL4208 P20618 Proteasome component C5 88.90% 90.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 88.40% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 87.98% 95.56%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 86.90% 95.50%
CHEMBL4040 P28482 MAP kinase ERK2 86.85% 83.82%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 86.15% 94.00%
CHEMBL340 P08684 Cytochrome P450 3A4 84.74% 91.19%
CHEMBL1293277 O15118 Niemann-Pick C1 protein 84.66% 81.11%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.60% 89.00%
CHEMBL5255 O00206 Toll-like receptor 4 81.52% 92.50%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.04% 94.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.79% 93.56%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 44818802
LOTUS LTS0071907
wikiData Q105233089