Alternarlactone A

Details

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Internal ID 14968465-e28b-4427-b15d-e9f273167052
Taxonomy Organoheterocyclic compounds > Benzoxepines > Dibenzoxepines
IUPAC Name (24R,27R)-8,14,20,27-tetrahydroxy-6,18-dimethoxy-24-methyl-11,16,23-trioxaoctacyclo[15.10.2.02,15.03,12.04,9.05,27.021,29.024,28]nonacosa-1(28),2(15),3(12),4(9),5,7,13,17,19,21(29)-decaene-10,22,26-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C29H18O12/c1-28-7-14(33)29(36)21-12(37-2)4-8(30)15-18(21)17-11(39-26(15)34)6-10(32)24-20(17)23(29)22(28)19-16(27(35)41-28)9(31)5-13(38-3)25(19)40-24/h4-6,30-32,36H,7H2,1-3H3/t28-,29+/m1/s1
InChI Key OFVMKRVGBKSDLT-WDYNHAJCSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C29H18O12
Molecular Weight 558.40 g/mol
Exact Mass 558.07982601 g/mol
Topological Polar Surface Area (TPSA) 178.00 Ų
XlogP 2.20

Synonyms

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(24R,27R)-8,14,20,27-tetrahydroxy-6,18-dimethoxy-24-methyl-11,16,23-trioxaoctacyclo[15.10.2.02,15.03,12.04,9.05,27.021,29.024,28]nonacosa-1(28),2(15),3(12),4(9),5,7,13,17,19,21(29)-decaene-10,22,26-trione
(24R,27R)-8,14,20,27-tetrahydroxy-6,18-dimethoxy-24-methyl-11,16,23-trioxaoctacyclo(15.10.2.02,15.03,12.04,9.05,27.021,29.024,28)nonacosa-1(28),2(15),3(12),4(9),5,7,13,17,19,21(29)-decaene-10,22,26-trione
RefChem:111536
CHEBI:226021

2D Structure

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2D Structure of Alternarlactone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.16% 91.11%
CHEMBL3192 Q9BY41 Histone deacetylase 8 96.83% 93.99%
CHEMBL240 Q12809 HERG 96.68% 89.76%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 96.51% 94.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.58% 95.56%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.23% 94.45%
CHEMBL2581 P07339 Cathepsin D 93.10% 98.95%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.01% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.76% 86.33%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.01% 89.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 87.61% 95.50%
CHEMBL4208 P20618 Proteasome component C5 87.54% 90.00%
CHEMBL4224 P49759 Dual specificty protein kinase CLK1 85.69% 85.30%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 85.61% 99.15%
CHEMBL1255126 O15151 Protein Mdm4 85.19% 90.20%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.72% 97.14%
CHEMBL3401 O75469 Pregnane X receptor 84.67% 94.73%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.07% 92.62%
CHEMBL2535 P11166 Glucose transporter 83.67% 98.75%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 83.65% 96.77%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 83.04% 96.67%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 82.63% 85.14%
CHEMBL230 P35354 Cyclooxygenase-2 82.60% 89.63%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.96% 97.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.79% 92.94%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146682085
LOTUS LTS0174640
wikiData Q105191421