Methyl (1R,2R)-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-1-naphthacenecarboxylate

Details

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Internal ID f943039e-4ab4-4278-ad18-fe0295335206
Taxonomy Benzenoids > Naphthacenes > Tetracenequinones
IUPAC Name methyl (1R,2R)-2-ethyl-2,5,7-trihydroxy-4,6,11-trioxo-1,3-dihydrotetracene-1-carboxylate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H18O8/c1-3-22(29)8-13(24)15-10(17(22)21(28)30-2)7-11-16(20(15)27)19(26)14-9(18(11)25)5-4-6-12(14)23/h4-7,17,23,27,29H,3,8H2,1-2H3/t17-,22+/m0/s1
InChI Key MHAXMIHGEZOCTQ-HTAPYJJXSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C22H18O8
Molecular Weight 410.40 g/mol
Exact Mass 410.10016753 g/mol
Topological Polar Surface Area (TPSA) 138.00 Ų
XlogP 3.20

Synonyms

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116235-59-7
S-383-Y
S 383-Y
CHEBI:75244
methyl (1R,2R)-2-ethyl-2,5,7-trihydroxy-4,6,11-trioxo-1,3-dihydrotetracene-1-carboxylate
methyl (1R,2R)-2-ethyl-2,5,7-trihydroxy-4,6,11-trioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate
1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-, methyl ester, (1R-trans)-
AC1L9FA0
SCHEMBL23251023
DTXSID40151323
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Methyl (1R,2R)-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-4,6,11-trioxo-1-naphthacenecarboxylate

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.29% 91.11%
CHEMBL2581 P07339 Cathepsin D 99.10% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.68% 96.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 96.35% 96.38%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 93.75% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.68% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.30% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.29% 99.23%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 88.99% 95.17%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.98% 93.03%
CHEMBL2535 P11166 Glucose transporter 86.40% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.25% 95.89%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 84.05% 96.21%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 83.41% 82.69%
CHEMBL4208 P20618 Proteasome component C5 82.71% 90.00%
CHEMBL340 P08684 Cytochrome P450 3A4 82.39% 91.19%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 81.93% 94.00%
CHEMBL226 P30542 Adenosine A1 receptor 81.49% 95.93%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 81.33% 96.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.10% 90.71%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.00% 91.07%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 443827
LOTUS LTS0076380
wikiData Q27105037