Aghardipeptin A

Details

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Internal ID 723340bb-b834-4ac8-861d-0265f24574f4
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name 9-(1H-imidazol-5-ylmethyl)-3,18-bis(1H-indol-3-ylmethyl)-12-(2-methylpropyl)-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracosane-2,5,8,11,14,17,20-heptone
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C43H51N11O7/c1-24(2)14-32-41(59)52-34(17-27-20-44-23-49-27)40(58)48-22-38(56)51-35(16-26-19-46-31-11-6-4-9-29(26)31)43(61)54-13-7-12-36(54)42(60)53-33(39(57)47-21-37(55)50-32)15-25-18-45-30-10-5-3-8-28(25)30/h3-6,8-11,18-20,23-24,32-36,45-46H,7,12-17,21-22H2,1-2H3,(H,44,49)(H,47,57)(H,48,58)(H,50,55)(H,51,56)(H,52,59)(H,53,60)
InChI Key RGZSNQSMWRPTNL-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C43H51N11O7
Molecular Weight 833.90 g/mol
Exact Mass 833.39729301 g/mol
Topological Polar Surface Area (TPSA) 255.00 Ų
XlogP 2.20

Synonyms

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DTXSID401333789

2D Structure

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2D Structure of Aghardipeptin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.21% 98.95%
CHEMBL3524 P56524 Histone deacetylase 4 99.13% 92.97%
CHEMBL333 P08253 Matrix metalloproteinase-2 98.96% 96.31%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.48% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.97% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 97.82% 97.64%
CHEMBL3310 Q96DB2 Histone deacetylase 11 97.43% 88.56%
CHEMBL1951 P21397 Monoamine oxidase A 97.33% 91.49%
CHEMBL5103 Q969S8 Histone deacetylase 10 97.00% 90.08%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.12% 91.11%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 94.78% 96.39%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 93.17% 90.71%
CHEMBL1937 Q92769 Histone deacetylase 2 93.08% 94.75%
CHEMBL4040 P28482 MAP kinase ERK2 93.06% 83.82%
CHEMBL255 P29275 Adenosine A2b receptor 92.08% 98.59%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.98% 95.56%
CHEMBL321 P14780 Matrix metalloproteinase 9 91.94% 92.12%
CHEMBL264 Q9Y5N1 Histamine H3 receptor 91.54% 91.43%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.15% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.40% 99.23%
CHEMBL3038469 P24941 CDK2/Cyclin A 90.30% 91.38%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.61% 97.25%
CHEMBL5203 P33316 dUTP pyrophosphatase 88.78% 99.18%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 88.48% 93.03%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 86.89% 99.09%
CHEMBL2535 P11166 Glucose transporter 86.28% 98.75%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 86.22% 83.10%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.15% 94.45%
CHEMBL228 P31645 Serotonin transporter 86.01% 95.51%
CHEMBL213 P08588 Beta-1 adrenergic receptor 85.77% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.71% 97.09%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 85.23% 82.38%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 85.18% 96.69%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.03% 89.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 84.49% 96.90%
CHEMBL1978 P11511 Cytochrome P450 19A1 84.42% 91.76%
CHEMBL2443 P49862 Kallikrein 7 84.32% 94.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 83.71% 93.99%
CHEMBL1902 P62942 FK506-binding protein 1A 83.45% 97.05%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 83.21% 88.42%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.68% 94.00%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 82.67% 93.40%
CHEMBL217 P14416 Dopamine D2 receptor 82.15% 95.62%
CHEMBL4073 P09237 Matrix metalloproteinase 7 80.74% 97.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 85246461
LOTUS LTS0076319
wikiData Q104196581