Aeruginosin KT608B

Details

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Internal ID 1c9355e8-2efc-49a9-b5e4-7f2460033e77
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
IUPAC Name (2R,3aR,6R,7aR)-N-[4-(diaminomethylideneamino)butyl]-6-hydroxy-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
SMILES (Canonical) C1CC(CC2C1CC(N2C(=O)C(CC3=CC=CC=C3)NC(=O)C(CC4=CC=C(C=C4)O)O)C(=O)NCCCCN=C(N)N)O
SMILES (Isomeric) C1C[C@H](C[C@@H]2[C@H]1C[C@@H](N2C(=O)[C@@H](CC3=CC=CC=C3)NC(=O)[C@@H](CC4=CC=C(C=C4)O)O)C(=O)NCCCCN=C(N)N)O
InChI InChI=1S/C32H44N6O6/c33-32(34)36-15-5-4-14-35-29(42)27-18-22-10-13-24(40)19-26(22)38(27)31(44)25(16-20-6-2-1-3-7-20)37-30(43)28(41)17-21-8-11-23(39)12-9-21/h1-3,6-9,11-12,22,24-28,39-41H,4-5,10,13-19H2,(H,35,42)(H,37,43)(H4,33,34,36)/t22-,24-,25-,26-,27-,28-/m1/s1
InChI Key HYPWKJJQJSEUDS-BYSSPFSSSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C32H44N6O6
Molecular Weight 608.70 g/mol
Exact Mass 608.33223314 g/mol
Topological Polar Surface Area (TPSA) 204.00 Ų
XlogP 1.30

Synonyms

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(2R,3aR,6R,7aR)-N-[4-(diaminomethylideneamino)butyl]-6-hydroxy-1-[(2R)-2-[[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
(2R,3aR,6R,7aR)-N-(4-(diaminomethylideneamino)butyl)-6-hydroxy-1-((2R)-2-(((2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl)amino)-3-phenylpropanoyl)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxamide
RefChem:109939
Aeruginosin KT 608B
CHEMBL2011687
CHEBI:223510
DTXSID201335327
1357382-04-7
(2R,3aR,6R,7aR)-N-(4-Carbamimidamidobutyl)-6-hydroxy-1-[(2R)-2-{[(2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoyl]amino}-3-phenylpropanoyl]octahydro-1H-indole-2-carboxamide

2D Structure

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2D Structure of Aeruginosin KT608B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.74% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 98.46% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.45% 96.09%
CHEMBL204 P00734 Thrombin 98.17% 96.01%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.01% 91.11%
CHEMBL221 P23219 Cyclooxygenase-1 97.13% 90.17%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 94.93% 96.67%
CHEMBL4227 P25090 Lipoxin A4 receptor 94.23% 100.00%
CHEMBL2514 O95665 Neurotensin receptor 2 93.68% 100.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 92.37% 97.64%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 92.12% 98.33%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.40% 95.89%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 90.98% 96.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.84% 95.56%
CHEMBL3060 Q9Y345 Glycine transporter 2 90.20% 99.17%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 89.96% 91.81%
CHEMBL1255126 O15151 Protein Mdm4 89.09% 90.20%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 88.61% 97.21%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 88.56% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 88.27% 97.09%
CHEMBL340 P08684 Cytochrome P450 3A4 88.16% 91.19%
CHEMBL2327 P21452 Neurokinin 2 receptor 87.71% 98.89%
CHEMBL3891 P07384 Calpain 1 86.73% 93.04%
CHEMBL5646 Q6L5J4 FML2_HUMAN 86.28% 100.00%
CHEMBL5028 O14672 ADAM10 86.08% 97.50%
CHEMBL2535 P11166 Glucose transporter 85.69% 98.75%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 85.64% 89.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.09% 90.71%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 82.92% 100.00%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 82.36% 97.29%
CHEMBL4101 P17612 cAMP-dependent protein kinase alpha-catalytic subunit 81.95% 82.86%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 81.56% 97.14%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 81.36% 89.33%
CHEMBL3902 P09211 Glutathione S-transferase Pi 81.26% 93.81%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 81.22% 96.03%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 81.13% 94.45%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 80.31% 82.69%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 80.18% 88.42%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 80.18% 96.25%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.16% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 57332918
LOTUS LTS0191414
wikiData Q77572707