Aeruginosin 205 A

Details

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Internal ID 3d4f9cd0-3028-4756-98ac-bf07cc290d3f
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Leucine and derivatives
IUPAC Name [1-[[(2R,3S)-1-[6-chloro-2-[4-(diaminomethylideneamino)butylcarbamoyl]-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-4-methyl-1-oxo-3-[(3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxypentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl] hydrogen sulfate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C34H53ClN6O12S/c1-18(2)29(52-33-28(44)27(43)24(42)17-51-33)26(40-31(46)25(53-54(48,49)50)14-19-8-4-3-5-9-19)32(47)41-22-16-21(35)11-10-20(22)15-23(41)30(45)38-12-6-7-13-39-34(36)37/h3-5,8-9,18,20-29,33,42-44H,6-7,10-17H2,1-2H3,(H,38,45)(H,40,46)(H4,36,37,39)(H,48,49,50)/t20?,21?,22?,23?,24-,25?,26-,27+,28-,29+,33?/m1/s1
InChI Key DZCMECJEYSAXKP-AJTMMEQZSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C34H53ClN6O12S
Molecular Weight 805.30 g/mol
Exact Mass 804.3130700 g/mol
Topological Polar Surface Area (TPSA) 294.00 Ų
XlogP -0.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Aeruginosin 205 A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.86% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 99.49% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.10% 96.09%
CHEMBL204 P00734 Thrombin 98.91% 96.01%
CHEMBL2179 P04062 Beta-glucocerebrosidase 95.59% 85.31%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 95.23% 98.33%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.99% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.29% 95.56%
CHEMBL5028 O14672 ADAM10 92.59% 97.50%
CHEMBL4227 P25090 Lipoxin A4 receptor 91.21% 100.00%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 90.91% 96.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 90.07% 97.14%
CHEMBL2514 O95665 Neurotensin receptor 2 89.78% 100.00%
CHEMBL221 P23219 Cyclooxygenase-1 89.52% 90.17%
CHEMBL4072 P07858 Cathepsin B 89.37% 93.67%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 89.23% 97.64%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 87.91% 95.83%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 87.50% 96.25%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 86.93% 95.89%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.72% 90.71%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.19% 96.47%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.98% 93.03%
CHEMBL3729 P22748 Carbonic anhydrase IV 85.84% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.17% 95.89%
CHEMBL4588 P22894 Matrix metalloproteinase 8 85.13% 94.66%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.94% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.82% 94.45%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 84.66% 89.67%
CHEMBL2327 P21452 Neurokinin 2 receptor 84.63% 98.89%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 84.47% 97.21%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.28% 93.56%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 83.15% 96.67%
CHEMBL5678 P34947 G protein-coupled receptor kinase 5 82.84% 88.00%
CHEMBL3891 P07384 Calpain 1 82.67% 93.04%
CHEMBL2959 Q08881 Tyrosine-protein kinase ITK/TSK 82.22% 95.00%
CHEMBL6136 O60341 Lysine-specific histone demethylase 1 82.06% 95.58%
CHEMBL3492 P49721 Proteasome Macropain subunit 81.72% 90.24%
CHEMBL3384 Q16512 Protein kinase N1 81.21% 80.71%
CHEMBL5646 Q6L5J4 FML2_HUMAN 80.74% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 80.51% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 139585583
LOTUS LTS0131409
wikiData Q77479362