Manumycin F

Details

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Internal ID 7764f58d-adaf-4e75-bab2-f46ceea64108
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Cyclic ketones > Cyclohexenones
IUPAC Name (2E,4E,6E)-7-cyclohexyl-N-[(5S)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]hepta-2,4,6-trienamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H34N2O7/c34-23-17-18-24(35)27(23)33-26(37)16-10-3-4-11-19-31(39)20-22(28(38)29-30(31)40-29)32-25(36)15-9-2-1-6-12-21-13-7-5-8-14-21/h1-4,6,9-12,15-16,19-21,29-30,34,39H,5,7-8,13-14,17-18H2,(H,32,36)(H,33,37)/b2-1+,4-3+,12-6+,15-9+,16-10+,19-11+/t29?,30?,31-/m0/s1
InChI Key SSHVAUUEPNULMP-FAYOCOEBSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C31H34N2O7
Molecular Weight 546.60 g/mol
Exact Mass 546.23660143 g/mol
Topological Polar Surface Area (TPSA) 145.00 Ų
XlogP 3.50

Synonyms

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(2E,4E,6E)-7-Cyclohexyl-N-[(5S)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]hepta-2,4,6-trienamide

2D Structure

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2D Structure of Manumycin F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.10% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.22% 95.56%
CHEMBL340 P08684 Cytochrome P450 3A4 90.16% 91.19%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 88.90% 93.04%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.88% 99.23%
CHEMBL1806 P11388 DNA topoisomerase II alpha 86.42% 89.00%
CHEMBL4530 P00488 Coagulation factor XIII 84.96% 96.00%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.63% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.44% 97.09%
CHEMBL241 Q14432 Phosphodiesterase 3A 83.14% 92.94%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.29% 92.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10030354
LOTUS LTS0071222
wikiData Q77518484